A Novel Bispecific Antibody for EpCAM-Directed Inhibition of the CD73/Adenosine Immune Checkpoint in Ovarian Cancer

SIMPLE SUMMARY: Blockade of the immunosuppressive CD73/ADO immune checkpoint has been suggested as a promising alternate immunotherapeutic approach for refractory ovarian cancer (OC). Despite promising preclinical results, midterm clinical trial reports indicate that the efficacy of the CD73-blockin...

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Detalles Bibliográficos
Autores principales: Ploeg, Emily Maria, Britsch, Isabel, van Wijngaarden, Anne Paulien, Ke, Xiurong, Hendriks, Mark Alexander Johannes Martinus, Samplonius, Douwe Freerk, Helfrich, Wijnand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378099/
https://www.ncbi.nlm.nih.gov/pubmed/37509310
http://dx.doi.org/10.3390/cancers15143651

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