Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy

Entry of antigen-specific T cells into human tumors is critical for immunotherapy, but the underlying mechanisms are poorly understood. Here, we combined high-dimensional spatial analyses with in vitro and in vivo modeling to study the mechanisms underlying immune infiltration in human multiple myel...

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Detalles Bibliográficos
Autores principales: Robinson, M. Hope, Villa, Nancy Y., Jaye, David L., Nooka, Ajay K., Duffy, Alyssa, McCachren, Samuel S., Manalo, Julia, Switchenko, Jeffrey M., Barnes, Sierra, Potdar, Sayalee, Azeem, Maryam I., Horvat, Ava A., Parihar, Vaunita C., Gong, Jingjing, Liang, Yan, Smith, Geoffrey H., Gupta, Vikas A., Boise, Lawrence H., Kaufman, Jonathan L., Hofmeister, Craig C., Joseph, Nisha S., Lonial, Sagar, Dhodapkar, Kavita M., Dhodapkar, Madhav V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378152/
https://www.ncbi.nlm.nih.gov/pubmed/37526080
http://dx.doi.org/10.1172/JCI167629

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