Ruxolitinib improves hematopoietic regeneration by restoring mesenchymal stromal cell function in acute graft-versus-host disease

Acute graft-versus-host disease (aGVHD) is a severe complication of allogeneic hematopoietic stem cell transplantation. Hematopoietic dysfunction accompanied by severe aGVHD, which may be caused by niche impairment, is a long-standing clinical problem. However, how the bone marrow (BM) niche is dama...

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Detalles Bibliográficos
Autores principales: Lin, Yan, Gu, Quan, Lu, Shihong, Pan, Zengkai, Yang, Zining, Li, Yapu, Yang, Shangda, Lv, Yanling, Zheng, Zhaofeng, Sun, Guohuan, Gou, Fanglin, Xu, Chang, Zhao, Xiangnan, Wang, Fengjiao, Wang, Chenchen, Yuan, Shiru, Xie, Xiaobao, Cao, Yang, Liu, Yue, Gu, Weiying, Cheng, Tao, Cheng, Hui, Hu, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378163/
https://www.ncbi.nlm.nih.gov/pubmed/37338986
http://dx.doi.org/10.1172/JCI162201

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