Cargando…
Targeting Prohibitins to Inhibit Melanoma Growth and Overcome Resistance to Targeted Therapies
Despite important advances in the treatment of metastatic melanoma with the development of MAPK-targeted agents and immune checkpoint inhibitors, the majority of patients either do not respond to therapies or develop acquired resistance. Furthermore, there is no effective targeted therapy currently...
Autores principales: | Najem, Ahmad, Krayem, Mohammad, Sabbah, Serena, Pesetti, Matilde, Journe, Fabrice, Awada, Ahmad, Désaubry, Laurent, Ghanem, Ghanem E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378173/ https://www.ncbi.nlm.nih.gov/pubmed/37508519 http://dx.doi.org/10.3390/cells12141855 |
Ejemplares similares
-
RTK Inhibitors in Melanoma: From Bench to Bedside
por: Sabbah, Malak, et al.
Publicado: (2021) -
Understanding Molecular Mechanisms of Phenotype Switching and Crosstalk with TME to Reveal New Vulnerabilities of Melanoma
por: Najem, Ahmad, et al.
Publicado: (2022) -
The benefit of co-targeting PARP-1 and c-Met on the efficacy of radiotherapy in wild type BRAF melanoma
por: Sabbah, Malak, et al.
Publicado: (2023) -
Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma
por: Krayem, Mohammad, et al.
Publicado: (2018) -
The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma
por: Krayem, Mohammad, et al.
Publicado: (2019)