Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth

CXCR7 is an atypical chemokine receptor that recruits β-arrestin (ARRB2) and internalizes into clathrin-coated intracellular vesicles where the complex acts as a scaffold for cytoplasmic kinase assembly and signal transduction. Here, we report that CXCR7 was elevated in the majority of prostate canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Gritsina, Galina, Fong, Ka-wing, Lu, Xiaodong, Lin, Zhuoyuan, Xie, Wanqing, Agarwal, Shivani, Lin, Dong, Schiltz, Gary E., Beltran, Himisha, Corey, Eva, Morrissey, Colm, Wang, Yuzhuo, Zhao, Jonathan C., Hussain, Maha, Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378179/
https://www.ncbi.nlm.nih.gov/pubmed/37347559
http://dx.doi.org/10.1172/JCI166248

Ejemplares similares

Ejemplares similares