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Mathematical Modeling of Clonal Interference by Density-Dependent Selection in Heterogeneous Cancer Cell Lines

Many cancer cell lines are aneuploid and heterogeneous, with multiple karyotypes co-existing within the same cell line. Karyotype heterogeneity has been shown to manifest phenotypically, thus affecting how cells respond to drugs or to minor differences in culture media. Knowing how to interpret kary...

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Detalles Bibliográficos
Autores principales: Veith, Thomas, Schultz, Andrew, Alahmari, Saeed, Beck, Richard, Johnson, Joseph, Andor, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378185/
https://www.ncbi.nlm.nih.gov/pubmed/37508513
http://dx.doi.org/10.3390/cells12141849