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Lactate Can Modulate the Antineoplastic Effects of Doxorubicin and Relieve the Drug’s Oxidative Damage on Cardiomyocytes
SIMPLE SUMMARY: Cancer cells are characterized by massive glucose consumption, leading to increased lactate generation. Once considered a waste product, this metabolite was recently shown to take part in the regulation of gene expression. The regulatory properties of lactate were also found to play...
Autores principales: | Rossi, Valentina, Govoni, Marzia, Di Stefano, Giuseppina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378253/ https://www.ncbi.nlm.nih.gov/pubmed/37509389 http://dx.doi.org/10.3390/cancers15143728 |
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