Cargando…
GBA Regulates EMT/MET and Chemoresistance in Squamous Cell Carcinoma Cells by Modulating the Cellular Glycosphingolipid Profile
Glycosphingolipids (GSL) are plasma membrane components that influence molecular processes involved in cancer initiation, progression, and therapeutic responses. They also modulate receptor tyrosine kinases involved in EMT. Therefore, understanding the mechanisms that regulate GSLs in cancer has imp...
Autores principales: | Clark, Laura E., Dickinson, Amanda J. G., Lima, Santiago |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378370/ https://www.ncbi.nlm.nih.gov/pubmed/37508550 http://dx.doi.org/10.3390/cells12141886 |
Ejemplares similares
-
Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model
por: Polinski, Nicole K., et al.
Publicado: (2021) -
Glycosphingolipid expression in squamous cell carcinoma of the upper aerodigestive tract
por: Filho, Marcilio Ferreira Marques, et al.
Publicado: (2015) -
Glycosphingolipid expression in squamous cell carcinoma of the upper aerodigestive tract
por: Filho, Marcilio Ferreira Marques, et al.
Publicado: (2015) -
Cellular and molecular events of inflammation induced transdifferentiation (EMT) and regeneration (MET) in mesenteric mesothelial cells
por: Zsiros, Viktória, et al.
Publicado: (2020) -
The Role of ROR1 in Chemoresistance and EMT in Endometrial Cancer Cells
por: Lee, Kyung-Jun, et al.
Publicado: (2023)