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Disruption of the Mammalian Ccr4–Not Complex Contributes to Transcription-Mediated Genome Instability
The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression. It is involved in the control of the cell cycle, chromatin modific...
Autores principales: | Hagkarim, Nafiseh Chalabi, Hajkarim, Morteza Chalabi, Suzuki, Toru, Fujiwara, Toshinobu, Winkler, G. Sebastiaan, Stewart, Grant S., Grand, Roger J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378556/ https://www.ncbi.nlm.nih.gov/pubmed/37508532 http://dx.doi.org/10.3390/cells12141868 |
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