Glutathione Programmed Mitochondria Targeted Delivery of Lonidamine for Effective Against Triple Negative Breast Cancer

INTRODUCTION: Mitochondria are a significant target of lonidamine (LND). However, its limited solubility and inability to specifically target mitochondria, LND can lead to hepatic toxicity and has shown only modest anticancer activity. The objective of this study is to establish a glutathione progra...

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Detalles Bibliográficos
Autores principales: Wang, Zhongjie, Qin, Yanru, Wang, Xueyuan, Zhang, Tianyu, Hu, Yixue, Wang, Dongna, Zhang, Liefeng, Zhu, Yongqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378575/
https://www.ncbi.nlm.nih.gov/pubmed/37520302
http://dx.doi.org/10.2147/IJN.S413217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378575/
https://www.ncbi.nlm.nih.gov/pubmed/37520302
http://dx.doi.org/10.2147/IJN.S413217

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