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Modulation of Lysosomal Cl(−) Mediates Migration and Apoptosis through the TRPML1 as a Lysosomal Cl(−) Sensor

Lysosomes are responsible for protein degradation and clearance in cellular recycling centers. It has been known that the lysosomal chloride level is enriched and involved in the intrinsic lysosomal function. However, the mechanism by which chloride levels can be sensed and that of the chloride-medi...

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Detalles Bibliográficos
Autores principales: Lee, Dongun, Hong, Jeong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378694/
https://www.ncbi.nlm.nih.gov/pubmed/37508500
http://dx.doi.org/10.3390/cells12141835