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Modulation of Lysosomal Cl(−) Mediates Migration and Apoptosis through the TRPML1 as a Lysosomal Cl(−) Sensor
Lysosomes are responsible for protein degradation and clearance in cellular recycling centers. It has been known that the lysosomal chloride level is enriched and involved in the intrinsic lysosomal function. However, the mechanism by which chloride levels can be sensed and that of the chloride-medi...
Autores principales: | Lee, Dongun, Hong, Jeong Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378694/ https://www.ncbi.nlm.nih.gov/pubmed/37508500 http://dx.doi.org/10.3390/cells12141835 |
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