In Vitro Analysis of the Effect of SARS-CoV-2 Non-VOC and four Variants of Concern on MHC-Class-I Expression on Calu-3 and Caco-2 Cells †

As the MHC-I-pathway is key to antigen presentation to cytotoxic T-cells and, therefore, recognition by the host adaptive immune system, we hypothesized that SARS-CoV-2 including its Variants of Concern (VOCs), influences MHC-I expression on epithelial cell surfaces as an immune evasion strategy. We...

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Detalles Bibliográficos
Autores principales: Bahlmann, Nora A., Mautner, Lena, Hoyos, Mona, Sallard, Erwan, Berger, Carola, Dangel, Alexandra, Jönsson, Franziska, Fischer, Johannes C., Kreppel, Florian, Zhang, Wenli, Esposito, Irene, Bölke, Edwin, Baiker, Armin, Ehrhardt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378856/
https://www.ncbi.nlm.nih.gov/pubmed/37510253
http://dx.doi.org/10.3390/genes14071348

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