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Synthetic Thioesters of Thiamine: Promising Tools for Slowing Progression of Neurodegenerative Diseases †

Thiamine (vitamin B1) is essential for the brain. This is attributed to the coenzyme role of thiamine diphosphate (ThDP) in glucose and energy metabolism. The synthetic thiamine prodrug, the thioester benfotiamine (BFT), has been extensively studied and has beneficial effects both in rodent models o...

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Detalles Bibliográficos
Autor principal: Bettendorff, Lucien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379298/
https://www.ncbi.nlm.nih.gov/pubmed/37511056
http://dx.doi.org/10.3390/ijms241411296