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Occurrence of L1M Elements in Chromosomal Rearrangements Associated to Chronic Myeloid Leukemia (CML): Insights from Patient-Specific Breakpoints Characterization
Chronic myeloid leukemia (CML) is a rare myeloproliferative disorder caused by the reciprocal translocation t(9;22)(q34;q11) in hematopoietic stem cells (HSCs). This chromosomal translocation results in the formation of an extra-short chromosome 22, called a Philadelphia chromosome (Ph), containing...
Autores principales: | L’Abbate, Alberto, Moretti, Vittoria, Pungolino, Ester, Micheloni, Giovanni, Valli, Roberto, Frattini, Annalisa, Barcella, Matteo, Acquati, Francesco, Reinbold, Rolland A, Costantino, Lucy, Ferrara, Fulvio, Trojani, Alessandra, Ventura, Mario, Porta, Giovanni, Cairoli, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379433/ https://www.ncbi.nlm.nih.gov/pubmed/37510256 http://dx.doi.org/10.3390/genes14071351 |
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