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Localization of Insertion Sequences in Plasmids for L-Cysteine Production in E. coli
Insertion sequence elements (ISE) are often found to be responsible for the collapse of production in synthetically engineered Escherichia coli. By the transposition of ISE into the open reading frame of the synthetic pathway, E. coli cells gain selection advantage over cells expressing the metaboli...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379815/ https://www.ncbi.nlm.nih.gov/pubmed/37510222 http://dx.doi.org/10.3390/genes14071317 |