Cargando…

Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy

Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment. Hydrogels enriched with nano-hydroxyapatite show potenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Omidian, Hossein, Chowdhury, Sumana Dey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379998/
https://www.ncbi.nlm.nih.gov/pubmed/37504412
http://dx.doi.org/10.3390/gels9070533
_version_ 1785080101015126016
author Omidian, Hossein
Chowdhury, Sumana Dey
author_facet Omidian, Hossein
Chowdhury, Sumana Dey
author_sort Omidian, Hossein
collection PubMed
description Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment. Hydrogels enriched with nano-hydroxyapatite show potential in bone regeneration, addressing challenges of bone defects, osteoporosis, and tumor-associated regeneration. In wound management and cancer therapy, they enable controlled release, accelerated wound closure, and targeted drug delivery. Injectable hydrogels also find applications in ischemic brain injury, tissue regeneration, cardiovascular diseases, and personalized cancer immunotherapy. This manuscript highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research. Moreover, it includes a perspective section that explores future prospects, emphasizes interdisciplinary collaboration, and underscores the promising future potential of injectable hydrogel nanocomposites in biomedical research and applications.
format Online
Article
Text
id pubmed-10379998
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103799982023-07-29 Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy Omidian, Hossein Chowdhury, Sumana Dey Gels Review Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment. Hydrogels enriched with nano-hydroxyapatite show potential in bone regeneration, addressing challenges of bone defects, osteoporosis, and tumor-associated regeneration. In wound management and cancer therapy, they enable controlled release, accelerated wound closure, and targeted drug delivery. Injectable hydrogels also find applications in ischemic brain injury, tissue regeneration, cardiovascular diseases, and personalized cancer immunotherapy. This manuscript highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research. Moreover, it includes a perspective section that explores future prospects, emphasizes interdisciplinary collaboration, and underscores the promising future potential of injectable hydrogel nanocomposites in biomedical research and applications. MDPI 2023-06-30 /pmc/articles/PMC10379998/ /pubmed/37504412 http://dx.doi.org/10.3390/gels9070533 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Omidian, Hossein
Chowdhury, Sumana Dey
Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
title Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
title_full Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
title_fullStr Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
title_full_unstemmed Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
title_short Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
title_sort advancements and applications of injectable hydrogel composites in biomedical research and therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10379998/
https://www.ncbi.nlm.nih.gov/pubmed/37504412
http://dx.doi.org/10.3390/gels9070533
work_keys_str_mv AT omidianhossein advancementsandapplicationsofinjectablehydrogelcompositesinbiomedicalresearchandtherapy
AT chowdhurysumanadey advancementsandapplicationsofinjectablehydrogelcompositesinbiomedicalresearchandtherapy