Cargando…
Sigma-1 Receptor Agonist Fluvoxamine Ameliorates Fibrotic Response of Trabecular Meshwork Cells
Primary open-angle glaucoma remains a global issue, lacking a definitive treatment. Increased intraocular pressure (IOP) is considered the primary risk factor of the disease and it can be caused by fibrotic-like changes in the trabecular meshwork (TM) such as increased tissue stiffness and outflow r...
Autores principales: | Hodrea, Judit, Tran, Minh Ngoc, Besztercei, Balazs, Medveczki, Timea, Szabo, Attila J., Orfi, Laszlo, Kovacs, Illes, Fekete, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380218/ https://www.ncbi.nlm.nih.gov/pubmed/37511406 http://dx.doi.org/10.3390/ijms241411646 |
Ejemplares similares
-
Sigma-1 Receptor Activation Is Protective against TGFβ2-Induced Extracellular Matrix Changes in Human Trabecular Meshwork Cells
por: Tran, Minh Ngoc, et al.
Publicado: (2023) -
A20 Attenuates the Fibrotic Response in the Trabecular Meshwork
por: Mzyk, Philip, et al.
Publicado: (2022) -
Reduced O-GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney
por: Hodrea, Judit, et al.
Publicado: (2020) -
Lyophilization and homogenization of biological samples improves reproducibility and reduces standard deviation in molecular biology techniques
por: Molnar, Agnes, et al.
Publicado: (2021) -
Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma
por: Zhavoronkov, Alex, et al.
Publicado: (2016)