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Atezolizumab Induces Necroptosis and Contributes to Hepatotoxicity of Human Hepatocytes

Atezolizumab is an immune checkpoint inhibitor (ICI) targeting PD-L1 for treatment of solid malignancies. Immune checkpoints control the immune tolerance, and the adverse events such as hepatotoxicity induced by ICIs are often considered as an immune-related adverse event (irAE). However, PD-L1 is a...

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Detalles Bibliográficos
Autores principales:	Endo, Yukinori, Winarski, Katie L., Sajib, Md Sanaullah, Ju, Anna, Wu, Wen Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380327/ https://www.ncbi.nlm.nih.gov/pubmed/37511454 http://dx.doi.org/10.3390/ijms241411694

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