Modulation of Mitochondrial Metabolic Parameters and Antioxidant Enzymes in Healthy and Glaucomatous Trabecular Meshwork Cells with Hybrid Small Molecule SA-2

Oxidative stress (OS)-induced mitochondrial damage is a risk factor for primary open-angle glaucoma (POAG). Mitochondria-targeted novel antioxidant therapies could unearth promising drug candidates for the management of POAG. Previously, our dual-acting hybrid molecule SA-2 with nitric oxide-donatin...

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Detalles Bibliográficos
Autores principales: Amankwa, Charles E., Young, Olivia, DebNath, Biddut, Gondi, Sudershan R., Rangan, Rajiv, Ellis, Dorette Z., Zode, Gulab, Stankowska, Dorota L., Acharya, Suchismita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380487/
https://www.ncbi.nlm.nih.gov/pubmed/37511316
http://dx.doi.org/10.3390/ijms241411557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380487/
https://www.ncbi.nlm.nih.gov/pubmed/37511316
http://dx.doi.org/10.3390/ijms241411557

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