Cargando…
Synthesis and Anti-Proliferative Activity of 5-Benzoyl and 5-Benzylhydroxy Derivatives of 3-Amino-2-Arylcarboxamido-Thieno[2-3-b]Pyridines
3-Amino-2-arylcarboxamido-thieno[2-3-b]pyridines have been previously described as having potent anti-proliferative activity against MDA-MB-231 and HCT116 cancer cell lines. The mechanism by which these molecules prevent cancer cell growth is proposed to be through interfering with phospholipid meta...
Autores principales: | Morphet, Bailey, Rees, Shaun W. P., Haverkate, Natalie A., Aziz, Hamid, Leung, Euphemia, Pilkington, Lisa I., Barker, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380547/ https://www.ncbi.nlm.nih.gov/pubmed/37511173 http://dx.doi.org/10.3390/ijms241411407 |
Ejemplares similares
-
Disruption of Crystal Packing in Thieno[2,3-b]pyridines Improves Anti-Proliferative Activity
por: Haverkate, Natalie A., et al.
Publicado: (2022) -
Tethered Aryl Groups Increase the Activity of Anti-Proliferative Thieno[2,3-b]Pyridines by Targeting a Lipophilic Region in the Active Site of PI-PLC
por: Haverkate, Natalie A., et al.
Publicado: (2021) -
Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents
por: Zafar, Ayesha, et al.
Publicado: (2018) -
GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents
por: Zafar, Ayesha, et al.
Publicado: (2017) -
Synthesis of some new Thieno[2,3-b]pyridines, Pyrimidino[4',5':4,5]thieno[2,3-b]pyridine and Pyridines Incorporating 5-Bromobenzofuran-2-yl Moiety
por: Abdelriheem, Nadia Abdelhamed, et al.
Publicado: (2015)