Distinct Molecular Signatures of Amyloid-Beta and Tau in Alzheimer’s Disease Associated with Down Syndrome

Limited comparative data exist on the molecular spectrum of amyloid-beta (Aβ) and tau deposition in individuals with Down syndrome (DS) and sporadic Alzheimer’s disease (sAD). We assessed Aβ and tau deposition severity in the temporal lobe and cerebellum of ten DS and ten sAD cases. Immunohistochemi...

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Detalles Bibliográficos
Autores principales: Ichimata, Shojiro, Martinez-Valbuena, Ivan, Lee, Seojin, Li, Jun, Karakani, Ali M., Kovacs, Gabor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380583/
https://www.ncbi.nlm.nih.gov/pubmed/37511361
http://dx.doi.org/10.3390/ijms241411596

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