Cargando…

Neurofilament-Light, a Promising Biomarker: Analytical, Metrological and Clinical Challenges

Neurofilament-light chain (Nf-L) is a non-specific early-stage biomarker widely studied in the context of neurodegenerative diseases (NDD) and traumatic brain injuries (TBI), which can be measured in biofluids after axonal damage. Originally measured by enzyme-linked immunosorbent assay (ELISA) in c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coppens, Salomé, Lehmann, Sylvain, Hopley, Christopher, Hirtz, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380627/ https://www.ncbi.nlm.nih.gov/pubmed/37511382 http://dx.doi.org/10.3390/ijms241411624

Ejemplares similares

Neurofilament Light Chain Is a Promising Biomarker in Alcohol Dependence
por: Li, Yanfei, et al.
Publicado: (2021)

Repeated neurofilament light chain measurements did not capture Riluzole therapeutic effect in amyotrophic lateral sclerosis patients
por: Esselin, Florence, et al.
Publicado: (2022)

Neurofilament light chain: defining the analyte
por: Leckey, Claire A., et al.
Publicado: (2022)

A Novel Neurofilament Light Chain ELISA Validated in Patients with Alzheimer’s Disease, Frontotemporal Dementia, and Subjective Cognitive Decline, and the Evaluation of Candidate Proteins for Immunoassay Calibration
por: Das, Shreyasee, et al.
Publicado: (2022)

Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson’s Disease
por: Pons, Marie-Laure, et al.
Publicado: (2022)

Neurofilament light chain is a promising serum biomarker in spinocerebellar ataxia type 3
por: Li, Quan-Fu, et al.
Publicado: (2019)

Neurofilaments in motor neuron disorders: towards promising diagnostic and prognostic biomarkers
por: Zucchi, Elisabetta, et al.
Publicado: (2020)

Neurofilament light: a narrative review on biomarker utility
por: Narayanan, Shilpa, et al.
Publicado: (2021)

Serum neurofilament light as a biomarker in progressive multiple sclerosis
por: Kapoor, Raju, et al.
Publicado: (2020)

Neurofilament light chain as a biomarker for diagnosis of multiple sclerosis
por: Kouchaki, Ebrahim, et al.
Publicado: (2021)

Analytical Challenges and Metrological Approaches to Ensuring Dietary Supplement Quality: International Perspectives
por: Durazzo, Alessandra, et al.
Publicado: (2022)

Neurofilament Light Chain in Adult and Pediatric Multiple Sclerosis: A Promising Biomarker to Better Characterize Disease Activity and Personalize MS Treatment
por: Ghezzi, Angelo, et al.
Publicado: (2023)

Neurofilament Light Chain Levels Are Predictive of Clinical Conversion in Radiologically Isolated Syndrome
por: Rival, Manon, et al.
Publicado: (2022)

Printed Electrochemical Biosensors: Opportunities and Metrological Challenges
por: Sardini, Emilio, et al.
Publicado: (2020)

Blood neurofilament light in remote settings: Alternative protocols to support sample collection in challenging pre‐analytical conditions
por: Simrén, Joel, et al.
Publicado: (2021)

Serum neurofilament light in MS: The first true blood-based biomarker?
por: Thebault, Simon, et al.
Publicado: (2021)

β-Synuclein as a candidate blood biomarker for synaptic degeneration in Alzheimer’s disease
por: Mohaupt, Pablo, et al.
Publicado: (2022)

Editorial: Proteomics as a Tool for Biomarker and Drug Target Discovery: Improving the Diagnosis and Treatment of Neurodegenerative Diseases
por: Belbin, Olivia, et al.
Publicado: (2020)

Circulating neurofilament light chain as a promising biomarker of AAV-induced dorsal root ganglia toxicity in nonclinical toxicology species
por: Fader, Kelly A., et al.
Publicado: (2022)

Neurofilament Light Chain as a Biomarker in Multiple Sclerosis
por: Varhaug, Kristin N., et al.
Publicado: (2019)

Neurofilament Light Chain as A Biomarker for Brain Metastases
por: Winther-Larsen, Anne, et al.
Publicado: (2020)

Antibodies to neurofilament light as potential biomarkers in multiple sclerosis
por: Puentes, Fabiola, et al.
Publicado: (2021)

Neurogranin and Neurofilament Light Chain as Preclinical Biomarkers in Scrapie
por: Betancor, Marina, et al.
Publicado: (2022)

Seven day pre-analytical stability of serum and plasma neurofilament light chain
por: Altmann, Patrick, et al.
Publicado: (2021)

A Comparison of Two Analytical Approaches for the Quantification of Neurofilament Light Chain, a Biomarker of Axonal Damage in Multiple Sclerosis
por: Pafiti, Anna, et al.
Publicado: (2023)

Blood Neurofilament Light Chain: The Neurologist’s Troponin?
por: Thebault, Simon, et al.
Publicado: (2020)

Neurofilament light chain: a biomarker for genetic frontotemporal dementia
por: Meeter, Lieke H., et al.
Publicado: (2016)

Neurofilament light as a blood biomarker for neurodegeneration in Down syndrome
por: Strydom, Andre, et al.
Publicado: (2018)

Neurofilament light and tau as blood biomarkers for sports-related concussion
por: Shahim, Pashtun, et al.
Publicado: (2018)

Neurofilament Light Chain: Blood Biomarker of Neonatal Neuronal Injury
por: Depoorter, Antoinette, et al.
Publicado: (2018)

Neurofilament Light Chain Is a Biomarker of Neurodegeneration in Ataxia Telangiectasia
por: Donath, H., et al.
Publicado: (2021)

Neurofilament light as a biomarker for motor decline in Parkinson’s disease
por: Liu, Yumei, et al.
Publicado: (2022)

Neurofilament Light Chain: A Candidate Biomarker of Perioperative Stroke
por: Zhang, Xiaoting, et al.
Publicado: (2022)

Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer’s disease and other proteinopathies
por: Mohaupt, Pablo, et al.
Publicado: (2023)

Clinical laboratory analytics: Challenges and promise for an emerging discipline
por: Shirts, Brian H., et al.
Publicado: (2015)

A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation
por: Gaetani, Lorenzo, et al.
Publicado: (2018)

Crowdsourcing as an Analytical Method: Metrology of Smartphone Measurements in Heritage Science
por: Brigham, Rosie, et al.
Publicado: (2018)

Neurofilaments contribution in clinic: state of the art
por: Delaby, Constance, et al.
Publicado: (2022)

Clinical quantitative MRI and the need for metrology
por: Cashmore, Matt T, et al.
Publicado: (2021)

Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep
por: Zetterberg, Henrik, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ajltn9oohnem3i8o5ktfomqkjq