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Repositioning of Anti-Diabetic Drugs against Dementia: Insight from Molecular Perspectives to Clinical Trials

Insulin resistance as a hallmark of type 2 DM (T2DM) plays a role in dementia by promoting pathological lesions or enhancing the vulnerability of the brain. Numerous studies related to insulin/insulin-like growth factor 1 (IGF-1) signaling are linked with various types of dementia. Brain insulin res...

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Detalles Bibliográficos
Autores principales: Mantik, Keren Esther Kristina, Kim, Sujin, Gu, Bonsang, Moon, Sohee, Kwak, Hyo-Bum, Park, Dong-Ho, Kang, Ju-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380685/
https://www.ncbi.nlm.nih.gov/pubmed/37511207
http://dx.doi.org/10.3390/ijms241411450