Novel Cellular Functions of ATR for Therapeutic Targeting: Embryogenesis to Tumorigenesis

The DNA damage response (DDR) is recognized as having an important role in cancer growth and treatment. ATR (ataxia telangiectasia mutated and Rad3-related) kinase, a major regulator of DDR, has shown significant therapeutic potential in cancer treatment. ATR inhibitors have shown anti-tumor effecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Biswas, Himadri, Makinwa, Yetunde, Zou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380702/
https://www.ncbi.nlm.nih.gov/pubmed/37511442
http://dx.doi.org/10.3390/ijms241411684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380702/
https://www.ncbi.nlm.nih.gov/pubmed/37511442
http://dx.doi.org/10.3390/ijms241411684

Ejemplares similares