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Novel Cellular Functions of ATR for Therapeutic Targeting: Embryogenesis to Tumorigenesis
The DNA damage response (DDR) is recognized as having an important role in cancer growth and treatment. ATR (ataxia telangiectasia mutated and Rad3-related) kinase, a major regulator of DDR, has shown significant therapeutic potential in cancer treatment. ATR inhibitors have shown anti-tumor effecti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380702/ https://www.ncbi.nlm.nih.gov/pubmed/37511442 http://dx.doi.org/10.3390/ijms241411684 |