Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells

Kinase Suppressor of RAS 1 (KSR1) is a scaffolding protein for the RAS-RAF-MEK-ERK pathway, which is one of the most frequently altered pathways in human cancers. Previous results have shown that KSR1 has a critical role in mutant RAS-mediated transformation. Here, we examined the role of KSR1 in mu...

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Detalles Bibliográficos
Autores principales: Liu, Zhi, Krstic, Aleksandar, Neve, Ashish, Casalou, Cristina, Rauch, Nora, Wynne, Kieran, Cassidy, Hilary, McCann, Amanda, Kavanagh, Emma, McCann, Brendan, Blanco, Alfonso, Rauch, Jens, Kolch, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
https://www.ncbi.nlm.nih.gov/pubmed/37511580
http://dx.doi.org/10.3390/ijms241411821

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