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GL-II-73, a Positive Allosteric Modulator of α5GABA(A) Receptors, Reverses Dopamine System Dysfunction Associated with Pilocarpine-Induced Temporal Lobe Epilepsy

Although seizures are a hallmark feature of temporal lobe epilepsy (TLE), psychiatric comorbidities, including psychosis, are frequently associated with TLE and contribute to decreased quality of life. Currently, there are no defined therapeutic protocols to manage psychosis in TLE patients, as anti...

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Detalles Bibliográficos
Autores principales: McCoy, Alexandra M., Prevot, Thomas D., Sharmin, Dishary, Cook, James M., Sibille, Etienne L., Lodge, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380722/
https://www.ncbi.nlm.nih.gov/pubmed/37511346
http://dx.doi.org/10.3390/ijms241411588