Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of Giardia lamblia: Biochemical and In Silico Characterization of a New Druggable Target

Giardiasis, which is caused by Giardia lamblia infection, is a relevant cause of morbidity and mortality worldwide. Because no vaccines are currently available to treat giardiasis, chemotherapeutic drugs are the main options for controlling infection. Evidence has shown that the nitro drug nitazoxan...

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Detalles Bibliográficos
Autores principales: Martínez-Rosas, Víctor, Hernández-Ochoa, Beatriz, Morales-Luna, Laura, Ortega-Cuellar, Daniel, González-Valdez, Abigail, Arreguin-Espinosa, Roberto, Rufino-González, Yadira, Calderón-Jaimes, Ernesto, Castillo-Rodríguez, Rosa Angélica, Wong-Baeza, Carlos, Baeza-Ramírez, Isabel, Pérez de la Cruz, Verónica, Vidal-Limón, Abraham, Gómez-Manzo, Saúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380810/
https://www.ncbi.nlm.nih.gov/pubmed/37511272
http://dx.doi.org/10.3390/ijms241411516

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