The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer

Endometrial cancer is one of the most common cancers in developing and developed countries. Although the detection of this cancer is high at the early stages, there is still a lack of markers to monitor the disease, its recurrence, and metastasis. MiRNAs are in charge of the post-transcriptional reg...

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Autores principales: Bogaczyk, Anna, Zawlik, Izabela, Zuzak, Tomasz, Kluz, Marta, Potocka, Natalia, Kluz, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380838/
https://www.ncbi.nlm.nih.gov/pubmed/37511248
http://dx.doi.org/10.3390/ijms241411489
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author Bogaczyk, Anna
Zawlik, Izabela
Zuzak, Tomasz
Kluz, Marta
Potocka, Natalia
Kluz, Tomasz
author_facet Bogaczyk, Anna
Zawlik, Izabela
Zuzak, Tomasz
Kluz, Marta
Potocka, Natalia
Kluz, Tomasz
author_sort Bogaczyk, Anna
collection PubMed
description Endometrial cancer is one of the most common cancers in developing and developed countries. Although the detection of this cancer is high at the early stages, there is still a lack of markers to monitor the disease, its recurrence, and metastasis. MiRNAs are in charge of the post-transcriptional regulation of genes responsible for the most important biological processes, which is why they are increasingly used as biomarkers in many types of cancer. Many studies have demonstrated the influence of miRNAs on the processes related to carcinogenesis. The characteristics of miRNA expression profiles in endometrial cancer will allow their use as diagnostic and prognostic biomarkers. This paper focuses on the discussion of selected miRNAs based on the literature and their role in the development of endometrial cancer.
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spelling pubmed-103808382023-07-29 The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer Bogaczyk, Anna Zawlik, Izabela Zuzak, Tomasz Kluz, Marta Potocka, Natalia Kluz, Tomasz Int J Mol Sci Review Endometrial cancer is one of the most common cancers in developing and developed countries. Although the detection of this cancer is high at the early stages, there is still a lack of markers to monitor the disease, its recurrence, and metastasis. MiRNAs are in charge of the post-transcriptional regulation of genes responsible for the most important biological processes, which is why they are increasingly used as biomarkers in many types of cancer. Many studies have demonstrated the influence of miRNAs on the processes related to carcinogenesis. The characteristics of miRNA expression profiles in endometrial cancer will allow their use as diagnostic and prognostic biomarkers. This paper focuses on the discussion of selected miRNAs based on the literature and their role in the development of endometrial cancer. MDPI 2023-07-15 /pmc/articles/PMC10380838/ /pubmed/37511248 http://dx.doi.org/10.3390/ijms241411489 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bogaczyk, Anna
Zawlik, Izabela
Zuzak, Tomasz
Kluz, Marta
Potocka, Natalia
Kluz, Tomasz
The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
title The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
title_full The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
title_fullStr The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
title_full_unstemmed The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
title_short The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
title_sort role of mirnas in the development, proliferation, and progression of endometrial cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380838/
https://www.ncbi.nlm.nih.gov/pubmed/37511248
http://dx.doi.org/10.3390/ijms241411489
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