Yersiniabactin-Producing E. coli Induces the Pyroptosis of Intestinal Epithelial Cells via the NLRP3 Pathway and Promotes Gut Inflammation

The high-pathogenicity island (HPI) was initially identified in Yersinia and can be horizontally transferred to Escherichia coli to produce yersiniabactin (Ybt), which enhances the pathogenicity of E. coli by competing with the host for Fe(3+). Pyroptosis is gasdermin-induced necrotic cell death. It...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Shan, Chun-Lang, Gao, Bin, Xiao, Jin-Long, Shen, Jue, Zhao, Jin-Gang, Han, Dong-Mei, Chen, Bin-Xun, Wang, Shuai, Liu, Gen, Xin, Ai-Guo, Lv, Long-Bao, Xiao, Peng, Gao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380849/
https://www.ncbi.nlm.nih.gov/pubmed/37511208
http://dx.doi.org/10.3390/ijms241411451

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