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Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population

The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors...

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Autores principales: Ferreira, Joana, Afonso, Julieta, Carneiro, Alexandre Lima, Vila, Isabel, Cunha, Cristina, Roque, Susana, Silva, Cristina, Mesquita, Amílcar, Cotter, Jorge, Correia-Neves, Margarida, Mansilha, Armando, Longatto-Filho, Adhemar, Cunha, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380901/
https://www.ncbi.nlm.nih.gov/pubmed/37504527
http://dx.doi.org/10.3390/jcdd10070271
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author Ferreira, Joana
Afonso, Julieta
Carneiro, Alexandre Lima
Vila, Isabel
Cunha, Cristina
Roque, Susana
Silva, Cristina
Mesquita, Amílcar
Cotter, Jorge
Correia-Neves, Margarida
Mansilha, Armando
Longatto-Filho, Adhemar
Cunha, Pedro
author_facet Ferreira, Joana
Afonso, Julieta
Carneiro, Alexandre Lima
Vila, Isabel
Cunha, Cristina
Roque, Susana
Silva, Cristina
Mesquita, Amílcar
Cotter, Jorge
Correia-Neves, Margarida
Mansilha, Armando
Longatto-Filho, Adhemar
Cunha, Pedro
author_sort Ferreira, Joana
collection PubMed
description The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors, anthropometric measures and medication. An observational and prospective study was conducted, and 177 subjects were included. Peri-aortic adipose tissue had the highest density, while the subcutaneous adipose tissue had the lowest. The density of subcutaneous adipose tissue differs from the density of visceral (p = 0.00) and peri-aortic adipose tissue (p = 0.00). Smokers/ex-smokers had a lower area (p = 0.00) and density (p = 0.02) of subcutaneous adipose tissue. Multiple linear regression analysis showed that sex was a predictor of subcutaneous adipose tissue area (β = −0.27, t = −3.12, p = 0.00) but smoking habits were not. After controlling for sex, we found that the association between smokers/ex-smokers and area of subcutaneous adipose tissue was lost, but the association with density persisted. Patients with hypertension had a higher visceral adipose tissue area, and this relationship was maintained even after adjusting for gender. Peri-aortic adipose tissue is similar to visceral and distinct from subcutaneous adipose tissue. Cardiovascular risk factors have different influences in distinct adipose compartments.
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spelling pubmed-103809012023-07-29 Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population Ferreira, Joana Afonso, Julieta Carneiro, Alexandre Lima Vila, Isabel Cunha, Cristina Roque, Susana Silva, Cristina Mesquita, Amílcar Cotter, Jorge Correia-Neves, Margarida Mansilha, Armando Longatto-Filho, Adhemar Cunha, Pedro J Cardiovasc Dev Dis Article The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors, anthropometric measures and medication. An observational and prospective study was conducted, and 177 subjects were included. Peri-aortic adipose tissue had the highest density, while the subcutaneous adipose tissue had the lowest. The density of subcutaneous adipose tissue differs from the density of visceral (p = 0.00) and peri-aortic adipose tissue (p = 0.00). Smokers/ex-smokers had a lower area (p = 0.00) and density (p = 0.02) of subcutaneous adipose tissue. Multiple linear regression analysis showed that sex was a predictor of subcutaneous adipose tissue area (β = −0.27, t = −3.12, p = 0.00) but smoking habits were not. After controlling for sex, we found that the association between smokers/ex-smokers and area of subcutaneous adipose tissue was lost, but the association with density persisted. Patients with hypertension had a higher visceral adipose tissue area, and this relationship was maintained even after adjusting for gender. Peri-aortic adipose tissue is similar to visceral and distinct from subcutaneous adipose tissue. Cardiovascular risk factors have different influences in distinct adipose compartments. MDPI 2023-06-25 /pmc/articles/PMC10380901/ /pubmed/37504527 http://dx.doi.org/10.3390/jcdd10070271 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ferreira, Joana
Afonso, Julieta
Carneiro, Alexandre Lima
Vila, Isabel
Cunha, Cristina
Roque, Susana
Silva, Cristina
Mesquita, Amílcar
Cotter, Jorge
Correia-Neves, Margarida
Mansilha, Armando
Longatto-Filho, Adhemar
Cunha, Pedro
Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
title Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
title_full Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
title_fullStr Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
title_full_unstemmed Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
title_short Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
title_sort exploring the diversity of visceral, subcutaneous and perivascular adipose tissue in a vascular surgery population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380901/
https://www.ncbi.nlm.nih.gov/pubmed/37504527
http://dx.doi.org/10.3390/jcdd10070271
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