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Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review

Nasal osteoblastoma (OB) is a rare and locally aggressive osteogenic tumor that has rarely been reported, and there is a lack of effective evidence data for its diagnosis and treatment. In this study, we report a 31-year-old female patient who presented with nasal congestion and associated progressi...

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Autores principales: Fang, Caishan, Wang, Ruizhi, Zhou, Min, Chen, Tengyu, Zhang, Qinxiu, Ruan, Yan, Li, Chunqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380942/
https://www.ncbi.nlm.nih.gov/pubmed/37519816
http://dx.doi.org/10.3389/fonc.2023.1168777
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author Fang, Caishan
Wang, Ruizhi
Zhou, Min
Chen, Tengyu
Zhang, Qinxiu
Ruan, Yan
Li, Chunqiao
author_facet Fang, Caishan
Wang, Ruizhi
Zhou, Min
Chen, Tengyu
Zhang, Qinxiu
Ruan, Yan
Li, Chunqiao
author_sort Fang, Caishan
collection PubMed
description Nasal osteoblastoma (OB) is a rare and locally aggressive osteogenic tumor that has rarely been reported, and there is a lack of effective evidence data for its diagnosis and treatment. In this study, we report a 31-year-old female patient who presented with nasal congestion and associated progressive painless swelling of the left maxillofacial region. A preoperative computed tomography (CT) examination of the paranasal sinuses was performed, and based on the imaging presentation, the surgeon was unable to differentiate between OB, osteoid osteoma (OO), fibrous dysplasia of bone (FDB) and osteoblastic fibroma (OF). After excluding contraindications to surgery, the patient underwent nasal endoscopic excision of the left nasal mass, which was found to be gravel-like and difficult to remove cleanly during the operation. The mass was brittle and bled easily, resulting in inadequate exposure of the operative field, prolonged operation time, and substantial intraoperative blood loss. This indicates that definite preoperative diagnosis (biopsy of deeper parts of the mass is recommended) and appropriate preoperative preparations (e.g., preoperative angiography and embolization, adequate blood preparation) are very important. The intraoperative frozen and postoperative pathological results clearly identified the tumor as OB. No local recurrence of the tumor was observed at the 11-month postoperative follow-up.
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spelling pubmed-103809422023-07-29 Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review Fang, Caishan Wang, Ruizhi Zhou, Min Chen, Tengyu Zhang, Qinxiu Ruan, Yan Li, Chunqiao Front Oncol Oncology Nasal osteoblastoma (OB) is a rare and locally aggressive osteogenic tumor that has rarely been reported, and there is a lack of effective evidence data for its diagnosis and treatment. In this study, we report a 31-year-old female patient who presented with nasal congestion and associated progressive painless swelling of the left maxillofacial region. A preoperative computed tomography (CT) examination of the paranasal sinuses was performed, and based on the imaging presentation, the surgeon was unable to differentiate between OB, osteoid osteoma (OO), fibrous dysplasia of bone (FDB) and osteoblastic fibroma (OF). After excluding contraindications to surgery, the patient underwent nasal endoscopic excision of the left nasal mass, which was found to be gravel-like and difficult to remove cleanly during the operation. The mass was brittle and bled easily, resulting in inadequate exposure of the operative field, prolonged operation time, and substantial intraoperative blood loss. This indicates that definite preoperative diagnosis (biopsy of deeper parts of the mass is recommended) and appropriate preoperative preparations (e.g., preoperative angiography and embolization, adequate blood preparation) are very important. The intraoperative frozen and postoperative pathological results clearly identified the tumor as OB. No local recurrence of the tumor was observed at the 11-month postoperative follow-up. Frontiers Media S.A. 2023-07-14 /pmc/articles/PMC10380942/ /pubmed/37519816 http://dx.doi.org/10.3389/fonc.2023.1168777 Text en Copyright © 2023 Fang, Wang, Zhou, Chen, Zhang, Ruan and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Fang, Caishan
Wang, Ruizhi
Zhou, Min
Chen, Tengyu
Zhang, Qinxiu
Ruan, Yan
Li, Chunqiao
Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
title Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
title_full Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
title_fullStr Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
title_full_unstemmed Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
title_short Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
title_sort refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10380942/
https://www.ncbi.nlm.nih.gov/pubmed/37519816
http://dx.doi.org/10.3389/fonc.2023.1168777
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