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One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study

There are increasing rates of cardiac surgery in the elderly. Frailty, depression, and social vulnerability are frequently present in older people, and should be considered while assessing risk and providing treatment options. We aimed to analyse the impact of clinically relevant variables on surviv...

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Autores principales: Castro, Maria de Lurdes, Alves, Marta, Papoila, Ana Luisa, Botelho, Amália, Fragata, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381118/
https://www.ncbi.nlm.nih.gov/pubmed/37510818
http://dx.doi.org/10.3390/jcm12144702
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author Castro, Maria de Lurdes
Alves, Marta
Papoila, Ana Luisa
Botelho, Amália
Fragata, José
author_facet Castro, Maria de Lurdes
Alves, Marta
Papoila, Ana Luisa
Botelho, Amália
Fragata, José
author_sort Castro, Maria de Lurdes
collection PubMed
description There are increasing rates of cardiac surgery in the elderly. Frailty, depression, and social vulnerability are frequently present in older people, and should be considered while assessing risk and providing treatment options. We aimed to analyse the impact of clinically relevant variables on survival at one year, and identify areas of future intervention. We performed a prospective cohort study at a University Hospital, with a sample of 309 elective cardiac surgery patients 65 years old and over. Their socio-demographic and clinical variables were collected. Frailty prevalence was 61.3%, while depression was absent in the majority of patients. Mortality was 1.6% and 7.8% at 30 days and 12 months, respectively. After Kaplan–Meier analysis, severe frailty (p = 0.003), severe depression (p = 0.027), pneumonia until 30 days (p = 0.014), and re-operation until 12 months (p = 0.003) significantly reduced survival, while social support increased survival (p = 0.004). In the adjusted multivariable Cox regression model, EuroSCORE II (HR = 1.27 [95% CI 1.069–1.499] p = 0.006), pneumonia until 30 days (HR = 4.19 [95% CI 1.169–15.034] p = 0.028), re-intervention until 12 months (HR = 3.14 [95% CI 1.091–9.056] p = 0.034), and social support (HR = 0.24 [95% CI 0.079–0.727] p = 0.012) explained time until death. Regular screening for social support, depression, and frailty adds relevant information regarding risk stratification, perioperative interventions, and decision-making in older people considered for cardiac surgery.
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spelling pubmed-103811182023-07-29 One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study Castro, Maria de Lurdes Alves, Marta Papoila, Ana Luisa Botelho, Amália Fragata, José J Clin Med Article There are increasing rates of cardiac surgery in the elderly. Frailty, depression, and social vulnerability are frequently present in older people, and should be considered while assessing risk and providing treatment options. We aimed to analyse the impact of clinically relevant variables on survival at one year, and identify areas of future intervention. We performed a prospective cohort study at a University Hospital, with a sample of 309 elective cardiac surgery patients 65 years old and over. Their socio-demographic and clinical variables were collected. Frailty prevalence was 61.3%, while depression was absent in the majority of patients. Mortality was 1.6% and 7.8% at 30 days and 12 months, respectively. After Kaplan–Meier analysis, severe frailty (p = 0.003), severe depression (p = 0.027), pneumonia until 30 days (p = 0.014), and re-operation until 12 months (p = 0.003) significantly reduced survival, while social support increased survival (p = 0.004). In the adjusted multivariable Cox regression model, EuroSCORE II (HR = 1.27 [95% CI 1.069–1.499] p = 0.006), pneumonia until 30 days (HR = 4.19 [95% CI 1.169–15.034] p = 0.028), re-intervention until 12 months (HR = 3.14 [95% CI 1.091–9.056] p = 0.034), and social support (HR = 0.24 [95% CI 0.079–0.727] p = 0.012) explained time until death. Regular screening for social support, depression, and frailty adds relevant information regarding risk stratification, perioperative interventions, and decision-making in older people considered for cardiac surgery. MDPI 2023-07-15 /pmc/articles/PMC10381118/ /pubmed/37510818 http://dx.doi.org/10.3390/jcm12144702 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Castro, Maria de Lurdes
Alves, Marta
Papoila, Ana Luisa
Botelho, Amália
Fragata, José
One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study
title One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study
title_full One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study
title_fullStr One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study
title_full_unstemmed One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study
title_short One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study
title_sort one-year survival after cardiac surgery in frail older people—social support matters: a prospective cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381118/
https://www.ncbi.nlm.nih.gov/pubmed/37510818
http://dx.doi.org/10.3390/jcm12144702
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