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Solid Lipid–Polymer Hybrid Nanoplatform for Topical Delivery of siRNA: In Vitro Biological Activity and Permeation Studies

Small interfering RNA (siRNA) molecules have limited transfection efficiency and stability, necessitating the use of delivery systems to be effective in gene knockdown therapies. In this regard, lipid–polymeric nanocarriers have emerged as a promising class of nanoparticles for siRNA delivery, parti...

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Detalles Bibliográficos
Autores principales: de Araujo, Margarete Moreno, Borgheti-Cardoso, Livia Neves, Praça, Fabíola Garcia, Marcato, Priscyla Daniely, Bentley, Maria Vitória Lopes Badra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381295/
https://www.ncbi.nlm.nih.gov/pubmed/37504869
http://dx.doi.org/10.3390/jfb14070374

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