The Establishment of a Tobramycin-Responsive Whole-Cell Micro-Biosensor Based on an Artificial Ribozyme Switch

In this study, a tobramycin concentration-dependent whole-cell micro-biosensor (tob-HHAz) was constructed by fusing a tobramycin aptamer with a hammerhead ribozyme (HHR) from Schistosoma mansoni. The biosensor was obtained by integrating all the modules into one complete RNA sequence, which was easi...

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Detalles Bibliográficos
Autores principales: Wang, Zhenzhen, Cheng, Jiawen, Dai, Guimin, Sun, Xiaoqi, Yin, Xueli, Zhang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381313/
https://www.ncbi.nlm.nih.gov/pubmed/37511928
http://dx.doi.org/10.3390/life13071553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381313/
https://www.ncbi.nlm.nih.gov/pubmed/37511928
http://dx.doi.org/10.3390/life13071553

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