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Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP
(1) Background: Transition is a planned movement of paediatric patients to adult healthcare systems, and its implementation is not yet established in all inflammatory bowel disease (IBD) units. The aim of the study was to evaluate the impact of transition on IBD outcomes. (2) Methods: Multicentre, r...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381381/ https://www.ncbi.nlm.nih.gov/pubmed/37510928 http://dx.doi.org/10.3390/jcm12144813 |
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author | Rubín de Célix, Cristina Martín-de-Carpi, Javier Pujol-Muncunill, Gemma Palomino, Laura María Velasco Rodríguez-Belvís, Marta Martín-Masot, Rafael Navas-López, Víctor Manuel Ricart, Elena Casanova, María José Rodríguez-Martínez, Alejandro Leo-Carnerero, Eduardo Alcaraz, Alba Mañosa, Miriam Hernández, Vicent Cobelas Cobelas, María Consuelo Sánchez, César Menchén, Luis Mesonero, Francisco Barreiro-De Acosta, Manuel Martinón-Torres, Nazareth Tejido Sandoval, Coral Rendo Vázquez, Alicia Corsino, Pilar Vicente, Raquel Hernández-Camba, Alejandro Alberto Alonso, José Ramón Alonso-Abreu, I. Castro Millán, Ana María Peries Reverter, Laia Castro, Beatriz Fernández-Salgado, Estela Busto Cuiñas, M. Mercedes Benítez, José Manuel Madero, Lucía Clemente, Fernando Riestra, Sabino Jiménez-Treviño, Santiago Boscá-Watts, Maia Crehuá-Gaudiza, Elena Calvo Moya, Marta Huguet, José María Largo-Blanco, Ester-María González Vives, Leticia Plaza, Rocío Guerra, Iván Barrio, Josefa Escartín, Laura Alfambra, Erika Cruz, Noelia Muñoz, M. Carmen Muñoz Pino, María Guadalupe Van Domselaar, Manuel Botella, Belén Monfort Miquel, David Rodríguez Grau, M. Carmen De La Mano, Agustín Ber, Yolanda Calvo Iñiguez, María Martínez-Pérez, Teresa de Jesús Chaparro, María Gisbert, Javier P. |
author_facet | Rubín de Célix, Cristina Martín-de-Carpi, Javier Pujol-Muncunill, Gemma Palomino, Laura María Velasco Rodríguez-Belvís, Marta Martín-Masot, Rafael Navas-López, Víctor Manuel Ricart, Elena Casanova, María José Rodríguez-Martínez, Alejandro Leo-Carnerero, Eduardo Alcaraz, Alba Mañosa, Miriam Hernández, Vicent Cobelas Cobelas, María Consuelo Sánchez, César Menchén, Luis Mesonero, Francisco Barreiro-De Acosta, Manuel Martinón-Torres, Nazareth Tejido Sandoval, Coral Rendo Vázquez, Alicia Corsino, Pilar Vicente, Raquel Hernández-Camba, Alejandro Alberto Alonso, José Ramón Alonso-Abreu, I. Castro Millán, Ana María Peries Reverter, Laia Castro, Beatriz Fernández-Salgado, Estela Busto Cuiñas, M. Mercedes Benítez, José Manuel Madero, Lucía Clemente, Fernando Riestra, Sabino Jiménez-Treviño, Santiago Boscá-Watts, Maia Crehuá-Gaudiza, Elena Calvo Moya, Marta Huguet, José María Largo-Blanco, Ester-María González Vives, Leticia Plaza, Rocío Guerra, Iván Barrio, Josefa Escartín, Laura Alfambra, Erika Cruz, Noelia Muñoz, M. Carmen Muñoz Pino, María Guadalupe Van Domselaar, Manuel Botella, Belén Monfort Miquel, David Rodríguez Grau, M. Carmen De La Mano, Agustín Ber, Yolanda Calvo Iñiguez, María Martínez-Pérez, Teresa de Jesús Chaparro, María Gisbert, Javier P. |
author_sort | Rubín de Célix, Cristina |
collection | PubMed |
description | (1) Background: Transition is a planned movement of paediatric patients to adult healthcare systems, and its implementation is not yet established in all inflammatory bowel disease (IBD) units. The aim of the study was to evaluate the impact of transition on IBD outcomes. (2) Methods: Multicentre, retrospective and observational study of IBD paediatric patients transferred to an adult IBD unit between 2017–2020. Two groups were compared: transition (≥1 joint visit involving the gastroenterologist, the paediatrician, a programme coordinator, the parents and the patient) and no-transition. Outcomes within one year after transfer were analysed. The main variable was poor clinical outcome (IBD flare, hospitalisation, surgery or any change in the treatment because of a flare). Predictive factors of poor clinical outcome were identified with multivariable analysis. (3) Results: A total of 278 patients from 34 Spanish hospitals were included. One hundred eighty-five patients (67%) from twenty-two hospitals (65%) performed a structured transition. Eighty-nine patients had poor clinical outcome at one year after transfer: 27% in the transition and 43% in the no-transition group (p = 0.005). One year after transfer, no-transition patients were more likely to have a flare (36% vs. 22%; p = 0.018) and reported more hospitalisations (10% vs. 3%; p = 0.025). The lack of transition, as well as parameters at transfer, including IBD activity, body mass index < 18.5 and corticosteroid treatment, were associated with poor clinical outcome. One patient in the transition group (0.4%) was lost to follow-up. (4) Conclusion: Transition care programmes improve patients’ outcomes after the transfer from paediatric to adult IBD units. Active IBD at transfer impairs outcomes. |
format | Online Article Text |
id | pubmed-10381381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103813812023-07-29 Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP Rubín de Célix, Cristina Martín-de-Carpi, Javier Pujol-Muncunill, Gemma Palomino, Laura María Velasco Rodríguez-Belvís, Marta Martín-Masot, Rafael Navas-López, Víctor Manuel Ricart, Elena Casanova, María José Rodríguez-Martínez, Alejandro Leo-Carnerero, Eduardo Alcaraz, Alba Mañosa, Miriam Hernández, Vicent Cobelas Cobelas, María Consuelo Sánchez, César Menchén, Luis Mesonero, Francisco Barreiro-De Acosta, Manuel Martinón-Torres, Nazareth Tejido Sandoval, Coral Rendo Vázquez, Alicia Corsino, Pilar Vicente, Raquel Hernández-Camba, Alejandro Alberto Alonso, José Ramón Alonso-Abreu, I. Castro Millán, Ana María Peries Reverter, Laia Castro, Beatriz Fernández-Salgado, Estela Busto Cuiñas, M. Mercedes Benítez, José Manuel Madero, Lucía Clemente, Fernando Riestra, Sabino Jiménez-Treviño, Santiago Boscá-Watts, Maia Crehuá-Gaudiza, Elena Calvo Moya, Marta Huguet, José María Largo-Blanco, Ester-María González Vives, Leticia Plaza, Rocío Guerra, Iván Barrio, Josefa Escartín, Laura Alfambra, Erika Cruz, Noelia Muñoz, M. Carmen Muñoz Pino, María Guadalupe Van Domselaar, Manuel Botella, Belén Monfort Miquel, David Rodríguez Grau, M. Carmen De La Mano, Agustín Ber, Yolanda Calvo Iñiguez, María Martínez-Pérez, Teresa de Jesús Chaparro, María Gisbert, Javier P. J Clin Med Article (1) Background: Transition is a planned movement of paediatric patients to adult healthcare systems, and its implementation is not yet established in all inflammatory bowel disease (IBD) units. The aim of the study was to evaluate the impact of transition on IBD outcomes. (2) Methods: Multicentre, retrospective and observational study of IBD paediatric patients transferred to an adult IBD unit between 2017–2020. Two groups were compared: transition (≥1 joint visit involving the gastroenterologist, the paediatrician, a programme coordinator, the parents and the patient) and no-transition. Outcomes within one year after transfer were analysed. The main variable was poor clinical outcome (IBD flare, hospitalisation, surgery or any change in the treatment because of a flare). Predictive factors of poor clinical outcome were identified with multivariable analysis. (3) Results: A total of 278 patients from 34 Spanish hospitals were included. One hundred eighty-five patients (67%) from twenty-two hospitals (65%) performed a structured transition. Eighty-nine patients had poor clinical outcome at one year after transfer: 27% in the transition and 43% in the no-transition group (p = 0.005). One year after transfer, no-transition patients were more likely to have a flare (36% vs. 22%; p = 0.018) and reported more hospitalisations (10% vs. 3%; p = 0.025). The lack of transition, as well as parameters at transfer, including IBD activity, body mass index < 18.5 and corticosteroid treatment, were associated with poor clinical outcome. One patient in the transition group (0.4%) was lost to follow-up. (4) Conclusion: Transition care programmes improve patients’ outcomes after the transfer from paediatric to adult IBD units. Active IBD at transfer impairs outcomes. MDPI 2023-07-21 /pmc/articles/PMC10381381/ /pubmed/37510928 http://dx.doi.org/10.3390/jcm12144813 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rubín de Célix, Cristina Martín-de-Carpi, Javier Pujol-Muncunill, Gemma Palomino, Laura María Velasco Rodríguez-Belvís, Marta Martín-Masot, Rafael Navas-López, Víctor Manuel Ricart, Elena Casanova, María José Rodríguez-Martínez, Alejandro Leo-Carnerero, Eduardo Alcaraz, Alba Mañosa, Miriam Hernández, Vicent Cobelas Cobelas, María Consuelo Sánchez, César Menchén, Luis Mesonero, Francisco Barreiro-De Acosta, Manuel Martinón-Torres, Nazareth Tejido Sandoval, Coral Rendo Vázquez, Alicia Corsino, Pilar Vicente, Raquel Hernández-Camba, Alejandro Alberto Alonso, José Ramón Alonso-Abreu, I. Castro Millán, Ana María Peries Reverter, Laia Castro, Beatriz Fernández-Salgado, Estela Busto Cuiñas, M. Mercedes Benítez, José Manuel Madero, Lucía Clemente, Fernando Riestra, Sabino Jiménez-Treviño, Santiago Boscá-Watts, Maia Crehuá-Gaudiza, Elena Calvo Moya, Marta Huguet, José María Largo-Blanco, Ester-María González Vives, Leticia Plaza, Rocío Guerra, Iván Barrio, Josefa Escartín, Laura Alfambra, Erika Cruz, Noelia Muñoz, M. Carmen Muñoz Pino, María Guadalupe Van Domselaar, Manuel Botella, Belén Monfort Miquel, David Rodríguez Grau, M. Carmen De La Mano, Agustín Ber, Yolanda Calvo Iñiguez, María Martínez-Pérez, Teresa de Jesús Chaparro, María Gisbert, Javier P. Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP |
title | Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP |
title_full | Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP |
title_fullStr | Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP |
title_full_unstemmed | Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP |
title_short | Benefits of Paediatric to Adult Transition Programme in Inflammatory Bowel Disease: The BUTTERFLY Study of GETECCU and SEGHNP |
title_sort | benefits of paediatric to adult transition programme in inflammatory bowel disease: the butterfly study of geteccu and seghnp |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381381/ https://www.ncbi.nlm.nih.gov/pubmed/37510928 http://dx.doi.org/10.3390/jcm12144813 |
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