Cargando…
Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis
(1) Background: Hand-assisted laparoscopic surgery (HALS) has engendered growing attention as a safe procedure for the resection of metastatic liver disease. However, there is little data available regarding the outcomes of HALS for colorectal liver metastasis (CRLM) in patients over the age of 75....
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381412/ https://www.ncbi.nlm.nih.gov/pubmed/37510900 http://dx.doi.org/10.3390/jcm12144785 |
_version_ | 1785080437415084032 |
---|---|
author | Mahamid, Ahmad Abu-Zaydeh, Omar Mattar, Samar Kazlow, Esther Froylich, Dvir Sawaied, Muneer Goldberg, Natalia Berger, Yael Sadot, Eran Haddad, Riad |
author_facet | Mahamid, Ahmad Abu-Zaydeh, Omar Mattar, Samar Kazlow, Esther Froylich, Dvir Sawaied, Muneer Goldberg, Natalia Berger, Yael Sadot, Eran Haddad, Riad |
author_sort | Mahamid, Ahmad |
collection | PubMed |
description | (1) Background: Hand-assisted laparoscopic surgery (HALS) has engendered growing attention as a safe procedure for the resection of metastatic liver disease. However, there is little data available regarding the outcomes of HALS for colorectal liver metastasis (CRLM) in patients over the age of 75. (2) Methods: We compare the short- and long-term outcomes of patients >75-years-old (defined in our study as “elderly patients” and referred to as group 1, G1), with patients <75-years-old (defined in our study as “younger patients” and referred to as group 2, G2). (3) Results: Of 145 patients, 28 were in G1 and 117 were in G2. The most common site of the primary tumor was the right colon in G1, and the left colon in G2 (p = 0.05). More patients in G1 underwent laparoscopic anterior segment resection compared with G2 (43% vs. 39% respectively) (p = 0.003). 53% of patients in G1 and 74% of patients in G2 completed neoadjuvant therapy (p = 0.04). The median size of the largest metastasis was 32 (IQR 19–52) mm in G1 and 20 (IQR 13–35) mm in G2 (p = 0.001). The rate of complications (Dindo-Clavien grade ≥ III) was slightly higher in G1 (p = 0.06). The overall 5-year survival was 30% in G1 and 52% in G2 (p = 0.12). (4) Conclusions: Hand-assisted laparoscopic surgery for colorectal liver metastasis is safe and effective in an elderly patient population. |
format | Online Article Text |
id | pubmed-10381412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103814122023-07-29 Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis Mahamid, Ahmad Abu-Zaydeh, Omar Mattar, Samar Kazlow, Esther Froylich, Dvir Sawaied, Muneer Goldberg, Natalia Berger, Yael Sadot, Eran Haddad, Riad J Clin Med Article (1) Background: Hand-assisted laparoscopic surgery (HALS) has engendered growing attention as a safe procedure for the resection of metastatic liver disease. However, there is little data available regarding the outcomes of HALS for colorectal liver metastasis (CRLM) in patients over the age of 75. (2) Methods: We compare the short- and long-term outcomes of patients >75-years-old (defined in our study as “elderly patients” and referred to as group 1, G1), with patients <75-years-old (defined in our study as “younger patients” and referred to as group 2, G2). (3) Results: Of 145 patients, 28 were in G1 and 117 were in G2. The most common site of the primary tumor was the right colon in G1, and the left colon in G2 (p = 0.05). More patients in G1 underwent laparoscopic anterior segment resection compared with G2 (43% vs. 39% respectively) (p = 0.003). 53% of patients in G1 and 74% of patients in G2 completed neoadjuvant therapy (p = 0.04). The median size of the largest metastasis was 32 (IQR 19–52) mm in G1 and 20 (IQR 13–35) mm in G2 (p = 0.001). The rate of complications (Dindo-Clavien grade ≥ III) was slightly higher in G1 (p = 0.06). The overall 5-year survival was 30% in G1 and 52% in G2 (p = 0.12). (4) Conclusions: Hand-assisted laparoscopic surgery for colorectal liver metastasis is safe and effective in an elderly patient population. MDPI 2023-07-20 /pmc/articles/PMC10381412/ /pubmed/37510900 http://dx.doi.org/10.3390/jcm12144785 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mahamid, Ahmad Abu-Zaydeh, Omar Mattar, Samar Kazlow, Esther Froylich, Dvir Sawaied, Muneer Goldberg, Natalia Berger, Yael Sadot, Eran Haddad, Riad Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
title | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
title_full | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
title_fullStr | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
title_full_unstemmed | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
title_short | Short- and Long-Term Outcomes in Elderly Patients Following Hand-Assisted Laparoscopic Surgery for Colorectal Liver Metastasis |
title_sort | short- and long-term outcomes in elderly patients following hand-assisted laparoscopic surgery for colorectal liver metastasis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381412/ https://www.ncbi.nlm.nih.gov/pubmed/37510900 http://dx.doi.org/10.3390/jcm12144785 |
work_keys_str_mv | AT mahamidahmad shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT abuzaydehomar shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT mattarsamar shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT kazlowesther shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT froylichdvir shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT sawaiedmuneer shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT goldbergnatalia shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT bergeryael shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT sadoteran shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis AT haddadriad shortandlongtermoutcomesinelderlypatientsfollowinghandassistedlaparoscopicsurgeryforcolorectallivermetastasis |