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Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography–Mass Spectrometry

The ergosterol pathway is a promising target for the development of new antifungals since its enzymes are essential for fungal cell growth. Appropriate screening assays are therefore needed that allow the identification of potential inhibitors. We developed a whole-cell screening method, which can b...

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Detalles Bibliográficos
Autores principales: Liebl, Maximilian, Huber, Ludwig, Elsaman, Hesham, Merschak, Petra, Wagener, Johannes, Gsaller, Fabio, Müller, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381423/
https://www.ncbi.nlm.nih.gov/pubmed/37504756
http://dx.doi.org/10.3390/jof9070768