Cargando…

Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography–Mass Spectrometry

The ergosterol pathway is a promising target for the development of new antifungals since its enzymes are essential for fungal cell growth. Appropriate screening assays are therefore needed that allow the identification of potential inhibitors. We developed a whole-cell screening method, which can b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liebl, Maximilian, Huber, Ludwig, Elsaman, Hesham, Merschak, Petra, Wagener, Johannes, Gsaller, Fabio, Müller, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381423/ https://www.ncbi.nlm.nih.gov/pubmed/37504756 http://dx.doi.org/10.3390/jof9070768

Ejemplares similares

The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus
por: Kühbacher, Alexander, et al.
Publicado: (2023)

Modular Inducible Multigene Expression System for Filamentous Fungi
por: Baldin, Clara, et al.
Publicado: (2022)

On the Origin of Isoprenoid Biosynthesis
por: Hoshino, Yosuke, et al.
Publicado: (2018)

Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae
por: Jordá, Tania, et al.
Publicado: (2020)

Characterization of the Ergosterol Biosynthesis Pathway in Ceratocystidaceae
por: Sayari, Mohammad, et al.
Publicado: (2021)

Five Questions about Non-Mevalonate Isoprenoid Biosynthesis
por: Odom, Audrey R.
Publicado: (2011)

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis
por: Edwards, Rachel L., et al.
Publicado: (2017)

Harnessing sub-organelle metabolism for biosynthesis of isoprenoids in yeast
por: Cao, Xuan, et al.
Publicado: (2020)

Gas chromatography and mass spectrometry : a practical guide
por: Kitson, Fulton G.
Publicado: (1996)

Gas chromatography and mass spectrometry : a practical guide /
por: Sparkman, O. David (Orrin David), 1942-
Publicado: (2011)

Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae
por: Chemler, Joseph A, et al.
Publicado: (2006)

Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis
por: KUZUYAMA, Tomohisa, et al.
Publicado: (2012)

Systematic Engineering for Improved Carbon Economy in the Biosynthesis of Polyhydroxyalkanoates and Isoprenoids
por: Zou, Huibin, et al.
Publicado: (2018)

Downregulation of Squalene Synthase Broadly Impacts Isoprenoid Biosynthesis in Guayule
por: Placido, Dante, et al.
Publicado: (2022)

Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles
por: Hu, Chengcheng, et al.
Publicado: (2018)

Linkage between genes involved in azole resistance and ergosterol biosynthesis
por: Moye-Rowley, W. Scott
Publicado: (2020)

Transcriptional regulation of ergosterol biosynthesis genes in response to iron deficiency
por: Jordá, Tania, et al.
Publicado: (2022)

The Effect of Honokiol on Ergosterol Biosynthesis and Vacuole Function in Candida albicans
por: Sun, Lingmei, et al.
Publicado: (2020)

The genome and transcriptome of Sarocladium terricola provide insight into ergosterol biosynthesis
por: Wang, Wei, et al.
Publicado: (2023)

An Improved Method to Quantify Short-Chain Fatty Acids in Biological Samples Using Gas Chromatography–Mass Spectrometry
por: Kim, Kyeong-Seog, et al.
Publicado: (2022)

Azole Resistance-Associated Regulatory Motifs within the Promoter of cyp51A in Aspergillus fumigatus
por: Kühbacher, Alexander, et al.
Publicado: (2022)

Genetic Profiling of the Isoprenoid and Sterol Biosynthesis Pathway Genes of Trypanosoma cruzi
por: Cosentino, Raúl O., et al.
Publicado: (2014)

Differential Subplastidial Localization and Turnover of Enzymes Involved in Isoprenoid Biosynthesis in Chloroplasts
por: Perello, Catalina, et al.
Publicado: (2016)

Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling
por: Castaño-Cerezo, Sara, et al.
Publicado: (2019)

Isoprenoid biosynthesis regulation in poplars by methylerythritol phosphate and mevalonic acid pathways
por: Movahedi, Ali, et al.
Publicado: (2022)

Biosynthesis of Chlorophyll and Other Isoprenoids in the Plastid of Red Grape Berry Skins
por: Teixeira, António, et al.
Publicado: (2023)

Small molecules inhibit growth, viability and ergosterol biosynthesis in Candida albicans
por: Rajput, Sandeep B, et al.
Publicado: (2013)

Transcriptome sequencing and gas chromatography–mass spectrometry analyses provide insights into β-caryophyllene biosynthesis in Brassica campestris
por: Wang, Haibin, et al.
Publicado: (2022)

Inducible Selectable Marker Genes to Improve Aspergillus fumigatus Genetic Manipulation
por: Baldin, Clara, et al.
Publicado: (2021)

Erratum to: “Gas chromatography-mass spectrometry in the taxonomy of Miscanthus”
por: Slynko, N.M., et al.
Publicado: (2020)

A RubisCO like protein links SAM metabolism with isoprenoid biosynthesis
por: Erb, Tobias J., et al.
Publicado: (2012)

New Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in Plasmodium
por: Saggu, Gagandeep S., et al.
Publicado: (2016)

Correction: Differential Subplastidial Localization and Turnover of Enzymes Involved in Isoprenoid Biosynthesis in Chloroplasts
por: Perello, Catalina, et al.
Publicado: (2022)

Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase
por: McCall, Laura-Isobel, et al.
Publicado: (2015)

Citronellal Exerts Its Antifungal Activity by Targeting Ergosterol Biosynthesis in Penicillium digitatum
por: OuYang, Qiuli, et al.
Publicado: (2021)

Erg4 Is Involved in Ergosterol Biosynthesis, Conidiation and Stress Response in Penicillium expansum
por: Han, Zhanhong, et al.
Publicado: (2023)

Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
por: Niu, Fu-Xing, et al.
Publicado: (2017)

Determination of cyclamate in urine by derivatized gas chromatography-mass spectrometry
por: Idris, Mohd, et al.
Publicado: (2013)

Characterization of Aroma Compounds in Cooked Sorghum Using Comprehensive Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry and Gas Chromatography-Olfactometry-Mass Spectrometry
por: Chen, Shuang, et al.
Publicado: (2021)

Development of Quantitative Chemical Ionization Using Gas Chromatography/Mass Spectrometry and Gas Chromatography/Tandem Mass Spectrometry for Ambient Nitro- and Oxy-PAHs and Its Applications
por: Jo, Jungmin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2anet76c443tns3h36imnrs3ri