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New Perspective for Drug–Drug Interaction in Perioperative Period

In this review, we aim to discuss current information on drug interactions in the perioperative period. During this period, patients receive several drugs that may interact with each other and affect the efficacy and safety of the treatment. There are three types of drug interactions: pharmacodynami...

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Autores principales: Silva, Abigail, Costa, Bárbara, Castro, Irene, Mourão, Joana, Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381519/
https://www.ncbi.nlm.nih.gov/pubmed/37510925
http://dx.doi.org/10.3390/jcm12144810
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author Silva, Abigail
Costa, Bárbara
Castro, Irene
Mourão, Joana
Vale, Nuno
author_facet Silva, Abigail
Costa, Bárbara
Castro, Irene
Mourão, Joana
Vale, Nuno
author_sort Silva, Abigail
collection PubMed
description In this review, we aim to discuss current information on drug interactions in the perioperative period. During this period, patients receive several drugs that may interact with each other and affect the efficacy and safety of the treatment. There are three types of drug interactions: pharmacodynamic, pharmacokinetic, and pharmaceutical. It is important to recognize that drug interactions may increase the toxicity of the drug or reduce its efficacy, increasing the risk of complications in the perioperative period. This review describes the most commonly used perioperative drugs approved by the FDA and some of the described interactions between them. Thoroughly reviewing a patient’s medication list and identifying potential interactions are essential steps in minimizing risks. Additionally, vigilant monitoring of patients during and after surgery plays a pivotal role in early detection of any signs of drug interactions. This article emphasizes the significance of addressing DDIs in the perioperative period to ensure patient well-being and advocates for the implementation of careful monitoring protocols to promptly identify and manage potential interactions.
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spelling pubmed-103815192023-07-29 New Perspective for Drug–Drug Interaction in Perioperative Period Silva, Abigail Costa, Bárbara Castro, Irene Mourão, Joana Vale, Nuno J Clin Med Review In this review, we aim to discuss current information on drug interactions in the perioperative period. During this period, patients receive several drugs that may interact with each other and affect the efficacy and safety of the treatment. There are three types of drug interactions: pharmacodynamic, pharmacokinetic, and pharmaceutical. It is important to recognize that drug interactions may increase the toxicity of the drug or reduce its efficacy, increasing the risk of complications in the perioperative period. This review describes the most commonly used perioperative drugs approved by the FDA and some of the described interactions between them. Thoroughly reviewing a patient’s medication list and identifying potential interactions are essential steps in minimizing risks. Additionally, vigilant monitoring of patients during and after surgery plays a pivotal role in early detection of any signs of drug interactions. This article emphasizes the significance of addressing DDIs in the perioperative period to ensure patient well-being and advocates for the implementation of careful monitoring protocols to promptly identify and manage potential interactions. MDPI 2023-07-21 /pmc/articles/PMC10381519/ /pubmed/37510925 http://dx.doi.org/10.3390/jcm12144810 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Silva, Abigail
Costa, Bárbara
Castro, Irene
Mourão, Joana
Vale, Nuno
New Perspective for Drug–Drug Interaction in Perioperative Period
title New Perspective for Drug–Drug Interaction in Perioperative Period
title_full New Perspective for Drug–Drug Interaction in Perioperative Period
title_fullStr New Perspective for Drug–Drug Interaction in Perioperative Period
title_full_unstemmed New Perspective for Drug–Drug Interaction in Perioperative Period
title_short New Perspective for Drug–Drug Interaction in Perioperative Period
title_sort new perspective for drug–drug interaction in perioperative period
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381519/
https://www.ncbi.nlm.nih.gov/pubmed/37510925
http://dx.doi.org/10.3390/jcm12144810
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