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Markers of Oxidative Stress in Patients with Acne: A Literature Review
Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with Cutibacterium acnes, and inflammation. The role of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381563/ https://www.ncbi.nlm.nih.gov/pubmed/37511808 http://dx.doi.org/10.3390/life13071433 |
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author | Popa, Gabriela Loredana Mitran, Cristina Iulia Mitran, Madalina Irina Tampa, Mircea Matei, Clara Popa, Mircea Ioan Georgescu, Simona Roxana |
author_facet | Popa, Gabriela Loredana Mitran, Cristina Iulia Mitran, Madalina Irina Tampa, Mircea Matei, Clara Popa, Mircea Ioan Georgescu, Simona Roxana |
author_sort | Popa, Gabriela Loredana |
collection | PubMed |
description | Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with Cutibacterium acnes, and inflammation. The role of oxidative stress (OS) has been intensively studied in inflammatory skin conditions such as psoriasis, vitiligo, or atopic dermatitis. However, the involvement of OS in the pathogenesis of acne is less known. The evidence accumulated over the last decade suggests that in the case of acne patients, there is an imbalance between oxidants and antioxidants. In this review, we analyzed studies that evaluated markers of OS in patients with acne, published in the last ten years, with the aim of providing new insights into the pathogenesis of acne. |
format | Online Article Text |
id | pubmed-10381563 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103815632023-07-29 Markers of Oxidative Stress in Patients with Acne: A Literature Review Popa, Gabriela Loredana Mitran, Cristina Iulia Mitran, Madalina Irina Tampa, Mircea Matei, Clara Popa, Mircea Ioan Georgescu, Simona Roxana Life (Basel) Review Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with Cutibacterium acnes, and inflammation. The role of oxidative stress (OS) has been intensively studied in inflammatory skin conditions such as psoriasis, vitiligo, or atopic dermatitis. However, the involvement of OS in the pathogenesis of acne is less known. The evidence accumulated over the last decade suggests that in the case of acne patients, there is an imbalance between oxidants and antioxidants. In this review, we analyzed studies that evaluated markers of OS in patients with acne, published in the last ten years, with the aim of providing new insights into the pathogenesis of acne. MDPI 2023-06-23 /pmc/articles/PMC10381563/ /pubmed/37511808 http://dx.doi.org/10.3390/life13071433 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Popa, Gabriela Loredana Mitran, Cristina Iulia Mitran, Madalina Irina Tampa, Mircea Matei, Clara Popa, Mircea Ioan Georgescu, Simona Roxana Markers of Oxidative Stress in Patients with Acne: A Literature Review |
title | Markers of Oxidative Stress in Patients with Acne: A Literature Review |
title_full | Markers of Oxidative Stress in Patients with Acne: A Literature Review |
title_fullStr | Markers of Oxidative Stress in Patients with Acne: A Literature Review |
title_full_unstemmed | Markers of Oxidative Stress in Patients with Acne: A Literature Review |
title_short | Markers of Oxidative Stress in Patients with Acne: A Literature Review |
title_sort | markers of oxidative stress in patients with acne: a literature review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381563/ https://www.ncbi.nlm.nih.gov/pubmed/37511808 http://dx.doi.org/10.3390/life13071433 |
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