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Markers of Oxidative Stress in Patients with Acne: A Literature Review

Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with Cutibacterium acnes, and inflammation. The role of...

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Autores principales: Popa, Gabriela Loredana, Mitran, Cristina Iulia, Mitran, Madalina Irina, Tampa, Mircea, Matei, Clara, Popa, Mircea Ioan, Georgescu, Simona Roxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381563/
https://www.ncbi.nlm.nih.gov/pubmed/37511808
http://dx.doi.org/10.3390/life13071433
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author Popa, Gabriela Loredana
Mitran, Cristina Iulia
Mitran, Madalina Irina
Tampa, Mircea
Matei, Clara
Popa, Mircea Ioan
Georgescu, Simona Roxana
author_facet Popa, Gabriela Loredana
Mitran, Cristina Iulia
Mitran, Madalina Irina
Tampa, Mircea
Matei, Clara
Popa, Mircea Ioan
Georgescu, Simona Roxana
author_sort Popa, Gabriela Loredana
collection PubMed
description Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with Cutibacterium acnes, and inflammation. The role of oxidative stress (OS) has been intensively studied in inflammatory skin conditions such as psoriasis, vitiligo, or atopic dermatitis. However, the involvement of OS in the pathogenesis of acne is less known. The evidence accumulated over the last decade suggests that in the case of acne patients, there is an imbalance between oxidants and antioxidants. In this review, we analyzed studies that evaluated markers of OS in patients with acne, published in the last ten years, with the aim of providing new insights into the pathogenesis of acne.
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spelling pubmed-103815632023-07-29 Markers of Oxidative Stress in Patients with Acne: A Literature Review Popa, Gabriela Loredana Mitran, Cristina Iulia Mitran, Madalina Irina Tampa, Mircea Matei, Clara Popa, Mircea Ioan Georgescu, Simona Roxana Life (Basel) Review Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with Cutibacterium acnes, and inflammation. The role of oxidative stress (OS) has been intensively studied in inflammatory skin conditions such as psoriasis, vitiligo, or atopic dermatitis. However, the involvement of OS in the pathogenesis of acne is less known. The evidence accumulated over the last decade suggests that in the case of acne patients, there is an imbalance between oxidants and antioxidants. In this review, we analyzed studies that evaluated markers of OS in patients with acne, published in the last ten years, with the aim of providing new insights into the pathogenesis of acne. MDPI 2023-06-23 /pmc/articles/PMC10381563/ /pubmed/37511808 http://dx.doi.org/10.3390/life13071433 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Popa, Gabriela Loredana
Mitran, Cristina Iulia
Mitran, Madalina Irina
Tampa, Mircea
Matei, Clara
Popa, Mircea Ioan
Georgescu, Simona Roxana
Markers of Oxidative Stress in Patients with Acne: A Literature Review
title Markers of Oxidative Stress in Patients with Acne: A Literature Review
title_full Markers of Oxidative Stress in Patients with Acne: A Literature Review
title_fullStr Markers of Oxidative Stress in Patients with Acne: A Literature Review
title_full_unstemmed Markers of Oxidative Stress in Patients with Acne: A Literature Review
title_short Markers of Oxidative Stress in Patients with Acne: A Literature Review
title_sort markers of oxidative stress in patients with acne: a literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381563/
https://www.ncbi.nlm.nih.gov/pubmed/37511808
http://dx.doi.org/10.3390/life13071433
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