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Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?

Obesity is an increasingly widespread disease worldwide because of lifestyle changes. It is associated with an increased risk of cardiovascular disease, primarily type 2 diabetes mellitus, with an increase in major cardiovascular adverse events. Bariatric surgery has been shown to be able to reduce...

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Autores principales: Bottino, Roberta, Carbone, Andreina, Formisano, Tiziana, D’Elia, Saverio, Orlandi, Massimiliano, Sperlongano, Simona, Molinari, Daniele, Castaldo, Pasquale, Palladino, Alberto, Barbareschi, Consiglia, Tolone, Salvatore, Docimo, Ludovico, Cimmino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381712/
https://www.ncbi.nlm.nih.gov/pubmed/37511927
http://dx.doi.org/10.3390/life13071552
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author Bottino, Roberta
Carbone, Andreina
Formisano, Tiziana
D’Elia, Saverio
Orlandi, Massimiliano
Sperlongano, Simona
Molinari, Daniele
Castaldo, Pasquale
Palladino, Alberto
Barbareschi, Consiglia
Tolone, Salvatore
Docimo, Ludovico
Cimmino, Giovanni
author_facet Bottino, Roberta
Carbone, Andreina
Formisano, Tiziana
D’Elia, Saverio
Orlandi, Massimiliano
Sperlongano, Simona
Molinari, Daniele
Castaldo, Pasquale
Palladino, Alberto
Barbareschi, Consiglia
Tolone, Salvatore
Docimo, Ludovico
Cimmino, Giovanni
author_sort Bottino, Roberta
collection PubMed
description Obesity is an increasingly widespread disease worldwide because of lifestyle changes. It is associated with an increased risk of cardiovascular disease, primarily type 2 diabetes mellitus, with an increase in major cardiovascular adverse events. Bariatric surgery has been shown to be able to reduce the incidence of obesity-related cardiovascular disease and thus overall mortality. This result has been shown to be the result of hormonal and metabolic effects induced by post-surgical anatomical changes, with important effects on multiple hormonal and molecular axes that make this treatment more effective than conservative therapy in determining a marked improvement in the patient’s cardiovascular risk profile. This review, therefore, aimed to examine the surgical techniques currently available and how these might be responsible not only for weight loss but also for metabolic improvement and cardiovascular benefits in patients undergoing such procedures.
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spelling pubmed-103817122023-07-29 Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver? Bottino, Roberta Carbone, Andreina Formisano, Tiziana D’Elia, Saverio Orlandi, Massimiliano Sperlongano, Simona Molinari, Daniele Castaldo, Pasquale Palladino, Alberto Barbareschi, Consiglia Tolone, Salvatore Docimo, Ludovico Cimmino, Giovanni Life (Basel) Review Obesity is an increasingly widespread disease worldwide because of lifestyle changes. It is associated with an increased risk of cardiovascular disease, primarily type 2 diabetes mellitus, with an increase in major cardiovascular adverse events. Bariatric surgery has been shown to be able to reduce the incidence of obesity-related cardiovascular disease and thus overall mortality. This result has been shown to be the result of hormonal and metabolic effects induced by post-surgical anatomical changes, with important effects on multiple hormonal and molecular axes that make this treatment more effective than conservative therapy in determining a marked improvement in the patient’s cardiovascular risk profile. This review, therefore, aimed to examine the surgical techniques currently available and how these might be responsible not only for weight loss but also for metabolic improvement and cardiovascular benefits in patients undergoing such procedures. MDPI 2023-07-13 /pmc/articles/PMC10381712/ /pubmed/37511927 http://dx.doi.org/10.3390/life13071552 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bottino, Roberta
Carbone, Andreina
Formisano, Tiziana
D’Elia, Saverio
Orlandi, Massimiliano
Sperlongano, Simona
Molinari, Daniele
Castaldo, Pasquale
Palladino, Alberto
Barbareschi, Consiglia
Tolone, Salvatore
Docimo, Ludovico
Cimmino, Giovanni
Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?
title Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?
title_full Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?
title_fullStr Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?
title_full_unstemmed Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?
title_short Cardiovascular Effects of Weight Loss in Obese Patients with Diabetes: Is Bariatric Surgery the Additional Arrow in the Quiver?
title_sort cardiovascular effects of weight loss in obese patients with diabetes: is bariatric surgery the additional arrow in the quiver?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381712/
https://www.ncbi.nlm.nih.gov/pubmed/37511927
http://dx.doi.org/10.3390/life13071552
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