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Surgical Approaches to Pancoast Tumors

Pancoast tumors, also defined as superior sulcus tumors, still represent a complex clinical condition requiring high technical surgical skills within more articulated multimodality treatment. The morbidity and mortality rates after Pancoast tumor treatments range from 10 to 55% and 0 to 7%, respecti...

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Autores principales: Petrella, Francesco, Casiraghi, Monica, Bertolaccini, Luca, Spaggiari, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381713/
https://www.ncbi.nlm.nih.gov/pubmed/37511781
http://dx.doi.org/10.3390/jpm13071168
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author Petrella, Francesco
Casiraghi, Monica
Bertolaccini, Luca
Spaggiari, Lorenzo
author_facet Petrella, Francesco
Casiraghi, Monica
Bertolaccini, Luca
Spaggiari, Lorenzo
author_sort Petrella, Francesco
collection PubMed
description Pancoast tumors, also defined as superior sulcus tumors, still represent a complex clinical condition requiring high technical surgical skills within more articulated multimodality treatment. The morbidity and mortality rates after Pancoast tumor treatments range from 10 to 55% and 0 to 7%, respectively, and the 5-year survival rate has significantly improved in recent years thanks to the advancement of treatments. Although a multimodality approach combining chemotherapy, radiotherapy, and surgery allows for radical resection and effective local control in the vast majority of patients, many patients cannot receive surgical resection or complete the whole programmed therapeutic regimen. Systemic relapse, particularly cerebral recurrence, still poses a significant issue in this cohort of patients. Surgical resection still plays a pivotal role within the multimodality approach. Here, we focus on surgical approaches to both anterior and posterior Pancoast tumors: the anterior transclavicular approach (Dartevelle); the anterior transmanubrial approach (Grunenwald–Spaggiari); the anterior trap-door approach (Masaoka, Nomori); the posterior approach (Shaw–Paulson); the hemiclamshell approach; and hybrid approaches. Global clinical condition, tumor histology, and long-term perspectives should always be taken into consideration when embarking on such a demanding oncologic scenario.
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spelling pubmed-103817132023-07-29 Surgical Approaches to Pancoast Tumors Petrella, Francesco Casiraghi, Monica Bertolaccini, Luca Spaggiari, Lorenzo J Pers Med Review Pancoast tumors, also defined as superior sulcus tumors, still represent a complex clinical condition requiring high technical surgical skills within more articulated multimodality treatment. The morbidity and mortality rates after Pancoast tumor treatments range from 10 to 55% and 0 to 7%, respectively, and the 5-year survival rate has significantly improved in recent years thanks to the advancement of treatments. Although a multimodality approach combining chemotherapy, radiotherapy, and surgery allows for radical resection and effective local control in the vast majority of patients, many patients cannot receive surgical resection or complete the whole programmed therapeutic regimen. Systemic relapse, particularly cerebral recurrence, still poses a significant issue in this cohort of patients. Surgical resection still plays a pivotal role within the multimodality approach. Here, we focus on surgical approaches to both anterior and posterior Pancoast tumors: the anterior transclavicular approach (Dartevelle); the anterior transmanubrial approach (Grunenwald–Spaggiari); the anterior trap-door approach (Masaoka, Nomori); the posterior approach (Shaw–Paulson); the hemiclamshell approach; and hybrid approaches. Global clinical condition, tumor histology, and long-term perspectives should always be taken into consideration when embarking on such a demanding oncologic scenario. MDPI 2023-07-21 /pmc/articles/PMC10381713/ /pubmed/37511781 http://dx.doi.org/10.3390/jpm13071168 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Petrella, Francesco
Casiraghi, Monica
Bertolaccini, Luca
Spaggiari, Lorenzo
Surgical Approaches to Pancoast Tumors
title Surgical Approaches to Pancoast Tumors
title_full Surgical Approaches to Pancoast Tumors
title_fullStr Surgical Approaches to Pancoast Tumors
title_full_unstemmed Surgical Approaches to Pancoast Tumors
title_short Surgical Approaches to Pancoast Tumors
title_sort surgical approaches to pancoast tumors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381713/
https://www.ncbi.nlm.nih.gov/pubmed/37511781
http://dx.doi.org/10.3390/jpm13071168
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