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Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). W...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381846/ https://www.ncbi.nlm.nih.gov/pubmed/37511925 http://dx.doi.org/10.3390/life13071550 |
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author | Ragusa, Alberto Brassetti, Aldo Prata, Francesco Iannuzzi, Andrea Callè, Pasquale Tedesco, Francesco Cacciatore, Loris Esperto, Francesco Simone, Giuseppe Scarpa, Roberto Mario Papalia, Rocco |
author_facet | Ragusa, Alberto Brassetti, Aldo Prata, Francesco Iannuzzi, Andrea Callè, Pasquale Tedesco, Francesco Cacciatore, Loris Esperto, Francesco Simone, Giuseppe Scarpa, Roberto Mario Papalia, Rocco |
author_sort | Ragusa, Alberto |
collection | PubMed |
description | Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). We retrospectively queried our datasets from May 2021 to May 2022. After the application of exclusion criteria, a total of 100 patients who underwent LARP for prostate cancer at our institution were enrolled. Through a sterile ruler inserted by a 12 mm trocar, the length of the membranous urethra spared during LARP was assessed intra-operatively. The baseline and peri- and postoperative data of patients were collected, and UC was defined as 0 or 1 on a safety pad. The median SULP was 20.5 mm (IQR, 14.5–25), and the median intraoperative EBL were 150 mL (IQR, 100–200). The Kaplan–Meier curve showed a significant difference at 20 mm, which was used as the cut-off value for SULP (log-rank test, p < 0.001). Multivariate Cox proportional hazards models showed that SULP and EBL < 250 mL were associated with UC recovery (all p < 0.02). Surgical urethral length preservation seemed to improve early UC recovery after LARP. Further multicentric studies are needed to confirm our findings. |
format | Online Article Text |
id | pubmed-10381846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103818462023-07-29 Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? Ragusa, Alberto Brassetti, Aldo Prata, Francesco Iannuzzi, Andrea Callè, Pasquale Tedesco, Francesco Cacciatore, Loris Esperto, Francesco Simone, Giuseppe Scarpa, Roberto Mario Papalia, Rocco Life (Basel) Article Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). We retrospectively queried our datasets from May 2021 to May 2022. After the application of exclusion criteria, a total of 100 patients who underwent LARP for prostate cancer at our institution were enrolled. Through a sterile ruler inserted by a 12 mm trocar, the length of the membranous urethra spared during LARP was assessed intra-operatively. The baseline and peri- and postoperative data of patients were collected, and UC was defined as 0 or 1 on a safety pad. The median SULP was 20.5 mm (IQR, 14.5–25), and the median intraoperative EBL were 150 mL (IQR, 100–200). The Kaplan–Meier curve showed a significant difference at 20 mm, which was used as the cut-off value for SULP (log-rank test, p < 0.001). Multivariate Cox proportional hazards models showed that SULP and EBL < 250 mL were associated with UC recovery (all p < 0.02). Surgical urethral length preservation seemed to improve early UC recovery after LARP. Further multicentric studies are needed to confirm our findings. MDPI 2023-07-13 /pmc/articles/PMC10381846/ /pubmed/37511925 http://dx.doi.org/10.3390/life13071550 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Ragusa, Alberto Brassetti, Aldo Prata, Francesco Iannuzzi, Andrea Callè, Pasquale Tedesco, Francesco Cacciatore, Loris Esperto, Francesco Simone, Giuseppe Scarpa, Roberto Mario Papalia, Rocco Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? |
title | Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? |
title_full | Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? |
title_fullStr | Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? |
title_full_unstemmed | Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? |
title_short | Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? |
title_sort | predictors of urinary continence recovery after laparoscopic-assisted radical prostatectomy: is surgical urethral length the only key factor? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381846/ https://www.ncbi.nlm.nih.gov/pubmed/37511925 http://dx.doi.org/10.3390/life13071550 |
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