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Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?

Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). W...

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Autores principales: Ragusa, Alberto, Brassetti, Aldo, Prata, Francesco, Iannuzzi, Andrea, Callè, Pasquale, Tedesco, Francesco, Cacciatore, Loris, Esperto, Francesco, Simone, Giuseppe, Scarpa, Roberto Mario, Papalia, Rocco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381846/
https://www.ncbi.nlm.nih.gov/pubmed/37511925
http://dx.doi.org/10.3390/life13071550
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author Ragusa, Alberto
Brassetti, Aldo
Prata, Francesco
Iannuzzi, Andrea
Callè, Pasquale
Tedesco, Francesco
Cacciatore, Loris
Esperto, Francesco
Simone, Giuseppe
Scarpa, Roberto Mario
Papalia, Rocco
author_facet Ragusa, Alberto
Brassetti, Aldo
Prata, Francesco
Iannuzzi, Andrea
Callè, Pasquale
Tedesco, Francesco
Cacciatore, Loris
Esperto, Francesco
Simone, Giuseppe
Scarpa, Roberto Mario
Papalia, Rocco
author_sort Ragusa, Alberto
collection PubMed
description Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). We retrospectively queried our datasets from May 2021 to May 2022. After the application of exclusion criteria, a total of 100 patients who underwent LARP for prostate cancer at our institution were enrolled. Through a sterile ruler inserted by a 12 mm trocar, the length of the membranous urethra spared during LARP was assessed intra-operatively. The baseline and peri- and postoperative data of patients were collected, and UC was defined as 0 or 1 on a safety pad. The median SULP was 20.5 mm (IQR, 14.5–25), and the median intraoperative EBL were 150 mL (IQR, 100–200). The Kaplan–Meier curve showed a significant difference at 20 mm, which was used as the cut-off value for SULP (log-rank test, p < 0.001). Multivariate Cox proportional hazards models showed that SULP and EBL < 250 mL were associated with UC recovery (all p < 0.02). Surgical urethral length preservation seemed to improve early UC recovery after LARP. Further multicentric studies are needed to confirm our findings.
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spelling pubmed-103818462023-07-29 Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor? Ragusa, Alberto Brassetti, Aldo Prata, Francesco Iannuzzi, Andrea Callè, Pasquale Tedesco, Francesco Cacciatore, Loris Esperto, Francesco Simone, Giuseppe Scarpa, Roberto Mario Papalia, Rocco Life (Basel) Article Several efforts in recent years have been made to predict urinary continence (UC) recovery after radical prostatectomy. The aim of our study was to investigate the impact of surgical urethral length preservation (SULP) on urinary continence after LARP (laparoscopic-assisted radical prostatectomy). We retrospectively queried our datasets from May 2021 to May 2022. After the application of exclusion criteria, a total of 100 patients who underwent LARP for prostate cancer at our institution were enrolled. Through a sterile ruler inserted by a 12 mm trocar, the length of the membranous urethra spared during LARP was assessed intra-operatively. The baseline and peri- and postoperative data of patients were collected, and UC was defined as 0 or 1 on a safety pad. The median SULP was 20.5 mm (IQR, 14.5–25), and the median intraoperative EBL were 150 mL (IQR, 100–200). The Kaplan–Meier curve showed a significant difference at 20 mm, which was used as the cut-off value for SULP (log-rank test, p < 0.001). Multivariate Cox proportional hazards models showed that SULP and EBL < 250 mL were associated with UC recovery (all p < 0.02). Surgical urethral length preservation seemed to improve early UC recovery after LARP. Further multicentric studies are needed to confirm our findings. MDPI 2023-07-13 /pmc/articles/PMC10381846/ /pubmed/37511925 http://dx.doi.org/10.3390/life13071550 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ragusa, Alberto
Brassetti, Aldo
Prata, Francesco
Iannuzzi, Andrea
Callè, Pasquale
Tedesco, Francesco
Cacciatore, Loris
Esperto, Francesco
Simone, Giuseppe
Scarpa, Roberto Mario
Papalia, Rocco
Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
title Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
title_full Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
title_fullStr Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
title_full_unstemmed Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
title_short Predictors of Urinary Continence Recovery after Laparoscopic-Assisted Radical Prostatectomy: Is Surgical Urethral Length the Only Key Factor?
title_sort predictors of urinary continence recovery after laparoscopic-assisted radical prostatectomy: is surgical urethral length the only key factor?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381846/
https://www.ncbi.nlm.nih.gov/pubmed/37511925
http://dx.doi.org/10.3390/life13071550
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