Synthesis of Altissimacoumarin D and Other Prenylated Coumarins and Their Ability to Reverse the Multidrug Resistance Phenotype in Candida albicans

Azoles are the main antifungal agents employed in clinical practice to treat invasive candidiasis. Nonetheless, their efficacy is limited by fungal resistance mechanisms, mainly the overexpression of efflux pumps. Consequently, candidiasis has a worrisome death rate of 75%. One potential strategy to...

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Detalles Bibliográficos
Autores principales: Silva, Anna Claudia, de Moraes, Daniel Clemente, do Carmo, Denilson Costa, Gomes, Giselle Cristina Casaes, Ganesan, A., Lopes, Rosangela Sabbatini Capella, Ferreira-Pereira, Antonio, Lopes, Cláudio Cerqueira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381857/
https://www.ncbi.nlm.nih.gov/pubmed/37504746
http://dx.doi.org/10.3390/jof9070758

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