Impact of Obesity and Bariatric Surgery on Metabolic Enzymes and P-Glycoprotein Activity Using the Geneva Cocktail Approach

The inter-individual variability of CYP450s enzyme activity may be reduced by comparing the effects of bariatric surgery on CYP-mediated drug elimination in comparable patients before and after surgery. The current research will use a low-dose phenotyping cocktail to simultaneously evaluate the acti...

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Detalles Bibliográficos
Autores principales: Ghasim, Hengameh, Rouini, Mohammadreza, Safari, Saeed, Larti, Farnoosh, Khoshayand, Mohammadreza, Gholami, Kheirollah, Neyshaburinezhad, Navid, Gloor, Yvonne, Daali, Youssef, Ardakani, Yalda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381895/
https://www.ncbi.nlm.nih.gov/pubmed/37511655
http://dx.doi.org/10.3390/jpm13071042

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