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Control of protein synthesis through mRNA pseudouridylation by dyskerin

Posttranscriptional modifications of mRNA have emerged as regulators of gene expression. Although pseudouridylation is the most abundant, its biological role remains poorly understood. Here, we demonstrate that the pseudouridine synthase dyskerin associates with RNA polymerase II, binds to thousands...

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Detalles Bibliográficos
Autores principales:	Pederiva, Chiara, Trevisan, Davide M., Peirasmaki, Dimitra, Chen, Shan, Savage, Sharon A., Larsson, Ola, Ule, Jernej, Baranello, Laura, Agostini, Federico, Farnebo, Marianne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381945/ https://www.ncbi.nlm.nih.gov/pubmed/37506213 http://dx.doi.org/10.1126/sciadv.adg1805

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