Association of 4qA-Specific Distal D4Z4 Hypomethylation With Disease Severity and Progression in Facioscapulohumeral Muscular Dystrophy

BACKGROUND AND OBJECTIVES: The objective of this study was to examine whether the regional methylation levels at the most distal D4Z4 repeat units (RU) in the 4qA-permissive haplotype were associated with disease severity and progression in facioscapulohumeral muscular dystrophy type 1 (FSHD1). METH...

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Detalles Bibliográficos
Autores principales: Zheng, Fuze, Qiu, Liangliang, Chen, Long, Zheng, Ying, Lin, Xiaodan, He, Junjie, Lin, Xin, He, Qifang, Lin, Yuhua, Lin, Lin, Wang, Lili, Lin, Feng, Yang, Kang, Lin, Minting, Lin, Yi, Fu, Ying, Wang, Ning, Wang, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382269/
https://www.ncbi.nlm.nih.gov/pubmed/37225433
http://dx.doi.org/10.1212/WNL.0000000000207418

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