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Transcription factors organize into functional groups on the linear genome and in 3D chromatin

Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial proximity (using chromatin conformation capture...

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Detalles Bibliográficos
Autores principales: Vadnala, Rakesh Netha, Hannenhalli, Sridhar, Narlikar, Leelavati, Siddharthan, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10382302/
https://www.ncbi.nlm.nih.gov/pubmed/37520992
http://dx.doi.org/10.1016/j.heliyon.2023.e18211